Electrophysiological subtypes and prognosis of Guillain–Barré syndrome in Northeastern China
Article first published online: 5 OCT 2012
Copyright © 2012 Wiley Periodicals, Inc.
Muscle & Nerve
Volume 47, Issue 1, pages 68–71, January 2013
How to Cite
Ye, Y., Wang, K., Deng, F. and Xing, Y. (2013), Electrophysiological subtypes and prognosis of Guillain–Barré syndrome in Northeastern China. Muscle Nerve, 47: 68–71. doi: 10.1002/mus.23477
- Issue published online: 15 DEC 2012
- Article first published online: 5 OCT 2012
- Accepted manuscript online: 18 JUN 2012 05:07AM EST
- Manuscript Accepted: 29 MAY 2012
- acute motor axonal neuropathy;
- acute inflammatory demyelinating polyneuropathy;
- Northeast China
The purpose of this study was to assess the electrophysiological subtypes and prognosis of Guillain–Barré syndrome (GBS) in northeastern China.
Ninety-nine patients with GBS were recruited between 2006 and 2010 and retrospectively reviewed.
Sixty-seven percent of patients had acute inflammatory demyelinating polyneuropathy (AIDP). Patients with acute motor axonal neuropathy (AMAN) had more severe symptoms at onset of GBS, and intravenous immunoglobulin (IVIg) was less effective in these patients. The prognosis may have been associated with the severity of the illness and did not differ between AMAN and AIDP patients. Abnormal motor nerve conduction studies (NCS) of the lower limbs and sensory NCS of the upper limbs with normal sural sensory nerve studies were the main electrophysiological features of AIDP.
AIDP is the main subtype of GBS, and it has specific electrophysiological characteristics in northeastern China. The prognosis of patients with AMAN was similar to that of patients with AIDP. Moreover, IVIg was more effective in patients with AIDP. Muscle Nerve, 2013