Quantitative muscle ultrasound and muscle force in healthy children: A 4-year follow-up study
Version of Record online: 20 MAR 2013
Copyright © 2012 Wiley Periodicals, Inc.
Muscle & Nerve
Volume 47, Issue 6, pages 856–863, June 2013
How to Cite
Jacobs, J., Jansen, M., Janssen, H., Raijmann, W., Van Alfen, N. and Pillen, S. (2013), Quantitative muscle ultrasound and muscle force in healthy children: A 4-year follow-up study. Muscle Nerve, 47: 856–863. doi: 10.1002/mus.23690
- Issue online: 23 MAY 2013
- Version of Record online: 20 MAR 2013
- Accepted manuscript online: 27 SEP 2012 03:21AM EST
- Manuscript Accepted: 20 SEP 2012
- neuromuscular disorder;
- muscle ultrasound;
- reference values
No longitudinal data on the normal development of muscle thickness (MT), quantitative muscle ultrasound echo intensity (EI), and muscle force (MF) in healthy children are yet available.
Reference values of MT, EI, and MF of 4 muscles from infancy to age 16 years were established during a 4-year follow-up period and correlated with age and growth.
For most muscles, MT and MF correlated with growth and aging, with almost equal influences of weight and height. EI increased only slightly (1% per year) with height, weight, and age.
To use these reference values for repeated measurements, MF and MT can be corrected for either weight or height. It does not seem necessary to correct EI for these factors during follow-up of a few years. These results provide a basis for more precise detection of changes in muscle structure or force in neuromuscular disorders. Muscle Nerve 47: 856–863, 2013