Serial cerebrospinal fluid neurofilament heavy chain levels in severe Guillain-Barré syndrome
Version of Record online: 28 MAY 2013
Copyright © 2012 Wiley Periodicals, Inc.
Muscle & Nerve
Volume 48, Issue 1, pages 132–134, July 2013
How to Cite
Dujmovic, I., Lunn, M. P., Reilly, M. M. and Petzold, A. (2013), Serial cerebrospinal fluid neurofilament heavy chain levels in severe Guillain-Barré syndrome. Muscle Nerve, 48: 132–134. doi: 10.1002/mus.23752
- Issue online: 21 JUN 2013
- Version of Record online: 28 MAY 2013
- Accepted manuscript online: 14 DEC 2012 02:43AM EST
- Manuscript Accepted: 10 DEC 2012
Additional Supporting Information may be found in the online version of this article.
SUPPLEMENTARY FIGURE 1. Hypothetical relationship of cerebrospinal fluid (CSF) NfHSMI35 levels (red boxes) and prognosis in Guillain-Barré syndrome (GBS). (A) In the acute phase, proximal axonotmesis within the CSF compartment causes high CSF NfHSMI35 levels and axonal loss follows. (B) Distal axonotmesis does not cause an increase of CSF NfHSMI35 levels, and there is a potential for recovery by axonal sprouting. (C) Failure of recovery from distal axonotmesis results in retrograde axonal degeneration showing a late increase of CSF NfHSMI35 levels. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]
Supplementary Table S1. Electrodiagnostic features of 3 patients with severe Guillain–Barré syndrome.
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