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SUPPLEMENTARY FIGURE 1. Hypothetical relationship of cerebrospinal fluid (CSF) NfHSMI35 levels (red boxes) and prognosis in Guillain-Barré syndrome (GBS). (A) In the acute phase, proximal axonotmesis within the CSF compartment causes high CSF NfHSMI35 levels and axonal loss follows. (B) Distal axonotmesis does not cause an increase of CSF NfHSMI35 levels, and there is a potential for recovery by axonal sprouting. (C) Failure of recovery from distal axonotmesis results in retrograde axonal degeneration showing a late increase of CSF NfHSMI35 levels. [Color figure can be viewed in the online issue, which is available at wileyonlinelibrary.com.]

Supplementary Table S1. Electrodiagnostic features of 3 patients with severe Guillain–Barré syndrome.

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