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Motor nerve impairment in diabetic patients with symmetrical distal sensory polyneuropathy: A single nerve fiber conduction velocity study

Authors

  • Gulin Sunter MD,

    1. Department of Neurology, Marmara University, Mimar Sinan Cad., Fevzi Çakmak Mah., Üst Kaynarca–Pendik, Istanbul, Turkey
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    • The first 2 authors (G.S. and K.U.) contributed equally to this study.

  • Kayihan Uluc MD,

    Corresponding author
    1. Department of Neurology, Marmara University, Mimar Sinan Cad., Fevzi Çakmak Mah., Üst Kaynarca–Pendik, Istanbul, Turkey
    • The first 2 authors (G.S. and K.U.) contributed equally to this study; therefore, they share first authorship.Correspondence to: K. Uluc; e-mail: kayihanu@yahoo.com

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  • Celal Salcini MD,

    1. Department of Neurology, Marmara University, Mimar Sinan Cad., Fevzi Çakmak Mah., Üst Kaynarca–Pendik, Istanbul, Turkey
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  • Cagri Mesut Temucin MD,

    1. Department of Neurology, Hacettepe University, Ankara, Turkey
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  • Orhan Yilmaz MD,

    1. Department of Neurology, Marmara University, Mimar Sinan Cad., Fevzi Çakmak Mah., Üst Kaynarca–Pendik, Istanbul, Turkey
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  • Tulin Tanridag MD,

    1. Department of Neurology, Marmara University, Mimar Sinan Cad., Fevzi Çakmak Mah., Üst Kaynarca–Pendik, Istanbul, Turkey
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  • Onder Us MD,

    1. Department of Neurology, Marmara University, Mimar Sinan Cad., Fevzi Çakmak Mah., Üst Kaynarca–Pendik, Istanbul, Turkey
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  • Luca Padua MD, PhD

    1. Department of Neurosciences, Universit̀ Cattolica, Roma, Italy
    2. Fondazione Don Gnocchi, Roma, Italy
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ABSTRACT

Introduction: In this study we investigated the clinical utility of single fiber conduction velocity (SF-CV) testing in the evaluation of motor nerve function in diabetic patients with signs and symptoms of symmetrical distal sensory polyneuropathy (DSP). SF-CV findings were compared with conventional nerve conduction studies (NCS). Methods: Twenty-eight consecutive type 2 diabetic patients with clinically diagnosed DSP were studied. Results: SF-CV testing of the tibial nerve was abnormal in 16 (57.1%) patients. Twelve patients with normal conventional motor NCS had abnormal findings by tibial SF-CV. SF-CV testing of the tibial nerve was significantly superior to all other motor NCS. Conclusions: SF-CV testing of the tibial nerve often demonstrates motor nerve impairment in diabetic patients with sensory DSP when conventional NCS are normal. Muscle Nerve 49: 84–89, 2014

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