This study was supported by the Institute for Performance Research, Manchester Metropolitan University.
Muscular adaptations and insulin-like growth factor-1 responses to resistance training are stretch-mediated
Version of Record online: 30 OCT 2013
Copyright © 2013 Wiley Periodicals, Inc.
Muscle & Nerve
Volume 49, Issue 1, pages 108–119, January 2014
How to Cite
McMahon, G., Morse, C. I., Burden, A., Winwood, K. and Onambélé, G. L. (2014), Muscular adaptations and insulin-like growth factor-1 responses to resistance training are stretch-mediated. Muscle Nerve, 49: 108–119. doi: 10.1002/mus.23884
- Issue online: 16 DEC 2013
- Version of Record online: 30 OCT 2013
- Accepted manuscript online: 27 APR 2013 07:33AM EST
- Manuscript Accepted: 15 APR 2013
- muscle architecture;
- range of motion;
- resistance training
Introduction: Modulation of muscle characteristics was attempted through altering muscle stretch during resistance training. We hypothesized that stretch would enhance muscle responses. Methods: Participants trained for 8 weeks, loading the quadriceps in a shortened (SL, 0–50° knee flexion; n = 10) or lengthened (LL, 40–90°; n = 11) position, followed by 4 weeks of detraining. Controls (CON; n = 10) were untrained. Quadriceps strength, vastus lateralis architecture, anatomical cross-sectional area (aCSA), and serum insulin-like growth factor-1 (IGF-1) were measured at weeks 0, 8, 10, and 12. Results: Increases in fascicle length (29 ± 4% vs. 14 ± 4%), distal aCSA (53 ± 12% vs. 18 ± 8%), strength (26 ± 6% vs. 7 ± 3%), and IGF-1 (31 ± 6% vs. 7 ± 6%) were greater in LL compared with SL muscles (P < 0.05). No changes occurred in CON. Detraining decrements in strength and aCSA were greater in SL than LL muscles (P < 0.05). Conclusions: Enhanced muscle in vivo (and somewhat IGF-1) adaptations to resistance training are concurrent with muscle stretch, which warrants its inclusion within training. Muscle Nerve 49: 108–119, 2014