The first 2 authors (Y.Y. and Y.T.) contributed equally to this study.
Muscle shear modulus measured with ultrasound shear-wave elastography across a wide range of contraction intensity
Article first published online: 17 MAY 2014
Copyright © 2013 Wiley Periodicals, Inc.
Muscle & Nerve
Volume 50, Issue 1, pages 103–113, July 2014
How to Cite
Yoshitake, Y., Takai, Y., Kanehisa, H. and Shinohara, M. (2014), Muscle shear modulus measured with ultrasound shear-wave elastography across a wide range of contraction intensity. Muscle Nerve, 50: 103–113. doi: 10.1002/mus.24104
This study was funded in part by the Japan Society of the Promotion of Science [Grant-in-Aid for Young Scientists (B) 23700774 to Y.T., and Grant-in-Aid for Scientific Research (B) 24300207 to Y.Y.].
- Issue published online: 19 JUN 2014
- Article first published online: 17 MAY 2014
- Accepted manuscript online: 23 OCT 2013 10:27PM EST
- Manuscript Accepted: 16 OCT 2013
- Manuscript Revised: 3 SEP 2013
- Manuscript Received: 23 JAN 2013
- biceps brachii;
- muscle tone;
- muscle stiffness
Introduction: In this study we examine the repeatability of measuring muscle shear modulus using ultrasound shear-wave elastography between trials and between days, and the association between shear modulus and contraction intensity over a wide range of intensities. Methods: Shear modulus of the biceps brachii was determined using ultrasound shear-wave elastography during static elbow flexion (up to 60% of maximal contraction) in healthy young adults. Results: The correspondence of shear modulus was confirmed in phantoms between the manufacturer-calibrated values and the shear-wave elastography values. The intraclass correlation coefficient of muscle shear modulus was high: 0.978 between trials and 0.948 between days. Shear modulus increased linearly with elbow flexion torque across contraction intensity, and its slope was associated negatively with muscle strength. Conclusions: Muscle shear modulus measured with ultrasound shear-wave elastography may be useful for inferring muscle stiffness across a wide range of contraction intensity. In addition, it has high repeatability between trials and between days. Muscle Nerve 50: 103–113, 2014