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Keywords:

  • Myasthenia gravis;
  • quality of life;
  • disability;
  • MG-QOL15;
  • modified Rankin Scale

Abstract

Introduction: We explored the modified Rankin Scale (mRS) as a tool to quantitate disability in myasthenia gravis (MG), to correlate patients' perception of their disability with that of the care provider and investigate its relation with other MG-related scores. Methods: We evaluated 107 MG patients at 2 neurological centers. Patients were assessed over the phone before and after clinic visits using the MG-QOL15 and mRS. At clinic, patients were assessed using the MG-QOL15, MG Composite (MGC), and mRS. Results: The MG-QOL15 correlated with the MGC, mRS, and assessors' scores of patients. Assessors' perception of disease burden was in line with that of the patients'. MG-QOL15 scores obtained over the phone were consistent with those obtained in clinic. Scores were generally higher in patients receiving steroids >5mg daily and in patients receiving or seeking benefits. Conclusion: The MG-QOL15 and mRS are useful in estimating disability in MG. © 2014 Wiley Periodicals, Inc.