Additional supporting information may be found in the online version of this article.

mus24262-sup-0001-suppappendix1.doc32KSupporting Information Appendix 1
mus24262-sup-0002-suppappendix2.pdf12KAppendix 2. Figure 3. PCR/RFLP analysis of muscle DNA from the patient (P) and a control (C). After digestion with Tsp509I, the normal pattern is two fragments of 145 and 63 bp, whereas, in the presence of the mutation, mtDNA is digested into four fragments of 145, 63, 34, and 29 bp. U, uncut fragment.

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