The effect of aerobic exercise on serum creatine kinase activities
Version of Record online: 13 OCT 2004
Copyright © 1986 John Wiley & Sons, Inc.
Muscle & Nerve
Volume 9, Issue 9, pages 820–824, November 1986
How to Cite
Nicholson, G. A., Morgan, G. J., Meerkin, M., Strauss, E. R. and McLeod, J. G. (1986), The effect of aerobic exercise on serum creatine kinase activities. Muscle Nerve, 9: 820–824. doi: 10.1002/mus.880090905
- Issue online: 13 OCT 2004
- Version of Record online: 13 OCT 2004
- Manuscript Accepted: 6 JAN 1986
- Manuscript Received: 9 JUL 1985
Aerobic exercise is now a common form of recreational exercise among young women. In a previous study, more than a third of a group of young mothers volunteering blood samples to establish a creatine kinase (CK) reference range for Duchenne muscular dystrophy (DMD) carrier detection regularly-participated in aerobic exercise programs. Aerobic exercise programs include eccentric exercises. As eccentric exercise is known to produce a delayed CK peak, this study was carried out to determine the effect of aerobic exercise on serum CK activities. The postexercise serum CK activity peak was monitored in 15 young women (age range 20–23 years) following aerobic exercise classes (45 minutes on 3 consecutive days). Peak values at 24–48 hours following the last class ranged from 90 to 3473 U/liter, or 1.55 to 34.71 times resting values. It is concluded that aerobic exercise programs should be excluded in order to obtain accurate resting serum CK values for muscle disease diagnosis.