Single fiber EMG reference values: A collaborative effort


  • List of participants: Coordinator–James M. Gilchrist, MD, Department of Neurology, Brown University, Providence, Rl; (in alphabetical order) Paul E. Barkhaus, MD, Department of Neurology, Minneapolis VA Medical Center, Minneapolis, MN; Vera Bril, MD, Division of Neurology, Toronto General Hospital, Toronto, Ontario, Canada; Jasper Daube, MD, Department of Neurology, Mayo Clinic, Rochester, MN; Jo DeMeirsman, MD, Department of Physical Medicine and Rehabilitation, University of Leuven, Leuven, Belgium; James F. Howard, Jr., MD, Department of Neurology, University of North Carolina, Chapel Hill, NC; Charles Jablecki, MD, Department of Neurosciences, University of California at San Diego, San Diego, CA; Donald B. Sanders, MD, Division of Neurology, Duke University, Durham, NC; Erik Stalberg, MD, Department of Clinical Neurophysiology, University of Uppsala, Uppsala, Sweden; Joze Trontelj, MD, Institute of Clinical Neurophysiology, University of Ljubljana, Ljubljana, Yugoslavia. Statistical analysis–John Pezzullo, PhD, Information Technology Center, Rhode Island Hospital, Providence, RI.


Single fiber electromyography (SFEMG) measurements of fiber density and jitter are used in the diagnosis of a variety of peripheral nervous system disorders. However, the normal values of these measurements for most muscles and age groups are not well documented in the literature. We present a retrospective and prospective multicenter collection of SFEMG jitter and fiber density data from control subjects obtained for the purpose of defining reference values for many muscles and different ages. The data and calculated upper limits for fiber density, individual pair jitter, and mean jitter are presented for each muscle in tabular and graphical format, for different age groups.