This paper is devoted to develop a theoretical framework to predict the macroscopic transversely isotropic elastoplastic behavior of clay-like material, which is viewed as a porous polycrystal. We consider evolutions of two local plastic mechanisms of grains and interface simultaneously, for which a Schmid criterion is used for the strength of sheet-like grains and a Tresca criterion for the strength of interfaces between particles. By adapting the standard incremental method, we propose firstly a classic self-consistent model, which does not consider the effect of interface, then a generalized self-consistent model in which the solid phase is represented by laminated (or isotropic) spherical grains surrounded by interfaces. Comparisons of numerical predictions between these two methods are performed and have demonstrated the validity of the generalized self-consistent model taking account of interface effects. Numerical simulations of uniaxial compression tests have shown that the macroscopic elastoplastic behavior of polycrystalline (clay-like) material can be successfully predicted by the way of considering the two local plastic mechanisms at microscopic scale. Copyright © 2013 John Wiley & Sons, Ltd.