Roger Dmochowski led the peer-review process as the Associate Editor responsible for the paper.
Original Clinical Article
Article first published online: 31 DEC 2012
Copyright © 2012 Wiley Periodicals, Inc.
Neurourology and Urodynamics
Volume 32, Issue 7, pages 1004–1009, September 2013
How to Cite
Opisso, E., Borau, A. and Rijkhoff, N. J.M. (2013), Subject-controlled stimulation of dorsal genital nerve to treat neurogenic detrusor overactivity at home. Neurourol. Urodyn., 32: 1004–1009. doi: 10.1002/nau.22359
Conflict of interest: none.
- Issue published online: 12 AUG 2013
- Article first published online: 31 DEC 2012
- Manuscript Accepted: 7 NOV 2012
- Manuscript Received: 25 JUN 2012
- dorsal genital nerve;
- electrical stimulation;
- urinary bladder;
- urinary incontinence
To investigate the effects of subject controlled dorsal genital nerve (DGN) electrical stimulation on neurogenic detrusor overactivity (NDO) in subjects at home.
Subjects underwent a 5-day study at home with DGN stimulation. Stimulation was provided with surface electrodes placed either on the dorsal penile shaft in males and on or close to the clitoris in females. The days 1 and 5 were with no stimulation whereas days 2–4 were with stimulation. Two urodynamic studies were performed at the beginning and at the end of the study. A bladder diary was obtained.
Eleven subjects with NDO and with urge incontinence were included. One subject stopped the protocol before the end of the 5-day trial and two did not undergo the second urodynamic study. The subjects showed a statistically significant increase in bladder capacities compared to baseline (P = 0.047). Mean volume per day voided significantly increased over the study within the subjects. Differences between day 1 and day 5 were statistically significant (P = 0.028).
The feasibility and the globally positive outcomes of the study indicate that the stimulation of the dorsal genital nerve can be an option for the treatment of the NDO. Neurourol. Urodynam. 32: 1004–1009, 2013. © 2012 Wiley Periodicals, Inc.