Mickey Karram led the peer-review process as the Associate Editor responsible for the paper.
Conceptual framework for patient-important treatment outcomes for pelvic organ prolapse
Version of Record online: 13 MAR 2013
© 2013 Wiley Periodicals, Inc.
Neurourology and Urodynamics
Volume 33, Issue 4, pages 414–419, April 2014
How to Cite
Sung, V. W., Rogers, R. G., Barber, M. D. and Clark, M. A. (2014), Conceptual framework for patient-important treatment outcomes for pelvic organ prolapse. Neurourol. Urodyn., 33: 414–419. doi: 10.1002/nau.22397
Conflict of Interest: None.
- Issue online: 3 APR 2014
- Version of Record online: 13 MAR 2013
- Manuscript Accepted: 15 FEB 2013
- Manuscript Received: 29 OCT 2012
- Eunice Kennedy Shriver National Institute of Child Health and Human Development. Grant Number: K23HD060665
- conceptual framework;
- focus group;
- outcome assessment;
- pelvic floor;
- quality of life;
- uterine prolapse;
- visceral prolapse
To develop a comprehensive conceptual framework representing the most important outcomes for women seeking treatment for pelvic organ prolapse (POP).
Twenty-five women with POP were recruited and participated in four semi-structured focus groups to refine and assess the content validity of a conceptual framework representing patient-important outcomes for POP. Specifically, the focus groups addressed the following three aims: (1) to evaluate the content and appropriateness of domains in our framework; (2) to identify gaps in the framework; and (3) to determine the relative importance of our framework domains from the patient perspective. Sessions were transcribed, coded, and qualitatively and quantitatively analyzed using analytic induction and deductive analysis to identify themes and domains relevant to women with POP.
Our focus groups confirmed the importance of vaginal bulge symptoms (discomfort, bother, and adaptation), and the overarching domains and subdomains of physical (physical function and participation), social (social function, relationships, and sexual function), and mental health (emotional distress, preoccupation, and body image). Patients ranked outcomes in the following order of importance: (1) the resolution of vaginal bulge symptoms, (2) improvement in physical function; (3) improvement in sexual function; (4) improvement in body image perception; and (5) improvement in social function.
We developed a conceptual framework for patient important outcomes of women seeking treatment for POP. This framework can improve the transparency and interpretation of POP study findings from the patient perspective. Vaginal bulge and its associated discomfort are most important for the definition of POP treatment success from the patient perspective. Neurourol. Urodynam. 33:414–419, 2014. © 2013 Wiley Periodicals, Inc.