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The relationship between BMI and urinary incontinence subgroups: Results from EpiLUTS

Authors


  • Heinz Koelbl led the peer-review process as the Associate Editor responsible for the paper.
  • Conflict of interest: Vik Khullar is a scientific consultant for Pfizer, Allergan, and Astellas; an investigator for Pfizer, Allergan, and Astellas; a lecturer for Pfizer, Astellas, and Novartis; and receives grant support from Pfizer and Astellas.
  • Ian Milsom is a scientific consultant for Pfizer and United BioSource; an investigator for Pfizer and Astellas; a lecturer for Pfizer, Astellas, and Novartis; and receives grant support from Pfizer and Astellas.
  • Caty Ebel Bitoun is an employee of Pfizer PIO.

Abstract

Aims

To evaluate the relationship between body mass index (BMI) and urinary incontinence (UI) in adults ≥40 from the United States, United Kingdom, and Sweden.

Methods

This was a secondary analysis of EpiLUTS—a population-representative, cross-sectional, Internet-based survey conducted to assess the prevalence and HRQL impact of urinary symptoms. UI was evaluated by the LUTS Tool and categorized by subgroups: no UI, urgency urinary incontinence (UUI), stress urinary incontinence (SUI), mixed urinary incontinence (MUI) (UUI + SUI), UUI + other UI (OI), SUI + OI, and OI. Descriptive statistics were used. Logistic regressions examined the relationship of BMI to UI controlling for demographics and comorbid conditions.

Results

Response rate was 59%; 10,070 men and 13,178 women were included. Significant differences in BMI were found across UI subgroups. Obesity rates were highest among those with MUI (men and women), SUI + OI (women), UUI and UUI + OI (men). Logistic regressions of each UI subgroup showed that BMI ≥ 30 (obese) was associated with UI in general and MUI (women) and UUI + OI (men). Among women, being obese increased the odds of having SUI and SUI + OI. Women with BMI 25–29.9 (overweight) were more likely to have UI in general and SUI with and without other incontinence (SUI, MUI, and SUI + OI). Being overweight was unrelated to any form of UI in men.

Conclusions

Results were consistent with prior research showing BMI is associated with higher risk of UI. These findings indicate substantial differences in obesity by gender and UI subtype, suggesting different mechanisms for UI other than purely mechanical stress on the bladder. Neurourol. Urodynam. 33:392–399, 2014. © 2013 Wiley Periodicals, Inc.

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