Christopher Chapple led the peer-review process as the Associate Editor responsible for the paper.
Fourth International Consultation on Incontinence - Research Society 2013
What is the role of covert infection in detrusor overactivity, and other LUTD? ICI-RS 2013
Version of Record online: 20 MAY 2014
© 2014 Wiley Periodicals, Inc.
Neurourology and Urodynamics
Volume 33, Issue 5, pages 606–610, June 2014
How to Cite
Moore, K. H. and Malykhina, A. P. (2014), What is the role of covert infection in detrusor overactivity, and other LUTD? ICI-RS 2013. Neurourol. Urodyn., 33: 606–610. doi: 10.1002/nau.22589
Conflict of interest: none.
- Issue online: 18 JUN 2014
- Version of Record online: 20 MAY 2014
- Manuscript Accepted: 25 FEB 2014
- Manuscript Received: 17 DEC 2013
- NHMRC. Grant Number: 527502
- NIH. Grant Numbers: DK077699, DK097819
- animal models;
- bacterial cystitis;
- covert infection;
- overactive bladder
A think tank was convened at the fourth ICI-RS meeting, which took place June 5–7, 2013 in Bristol UK, to consider current evidence and controversies surrounding the possible role of ‘covert infection’ in the pathophysiology of refractory detrusor overactivity (DO) and other lower urinary tract disorders (LUTD). The topic was chosen because several authors from different centers worldwide have recently published evidence which supports this concept. However, to date there is inconsistency regarding terminology and microbiological definitions, which were discussed by the participants. The mechanisms whereby infection/inflammation could actually promote aberrant detrusor contractions in the human remain controversial, and are more fully described in this report. Future requirements for research into this topic were outlined. Neurourol. Urodynam. 33:606–610, 2014. © 2014 Wiley Periodicals, Inc.