Review Article
You have free access to this content
Diffusion tensor imaging of normal and injured developing human brain - a technical review
Article first published online: 5 DEC 2002
DOI: 10.1002/nbm.784
Copyright © 2002 John Wiley & Sons, Ltd.
Issue
1099-1492/asset/cover.gif?v=1&s=7f88958d6a8e1ce4e85055c646c8110c2575d407)
NMR in Biomedicine
Special Issue: Diffusion tensor imaging and axonal mapping - state of the art
Volume 15, Issue 7-8, pages 543–552, November - December 2002
Additional Information
How to Cite
Neil, J., Miller, J., Mukherjee, P. and Hüppi, P. S. (2002), Diffusion tensor imaging of normal and injured developing human brain - a technical review. NMR Biomed., 15: 543–552. doi: 10.1002/nbm.784
Publication History
- Issue published online: 5 DEC 2002
- Article first published online: 5 DEC 2002
- Manuscript Accepted: 5 SEP 2001
- Manuscript Revised: 22 AUG 2001
- Manuscript Received: 16 MAY 2001
Funded by
- NIH. Grant Number: NS37357
- Swiss National Foundation. Grant Number: 32-56927.99
- Sigrist Foundation of the University of Berne
REFERENCES
- 1, , , , , . Identification of “premyelination” by diffusion-weighted MRI. J. Comput. Assist. Tomogr. 1995; 19: 28–33.
- 2, , , , , , . Microstructural development of human newborn cerebral white matter assessed in vivo by diffusion tensor magnetic resonance imaging. Pediatr. Res. 1998; 44: 584–590.
- 3, , , , , , , , , , . Normal brain in human newborns: Apparent diffusion coefficient and diffusion anisotropy measured using diffusion tensor imaging. Radiology 1998; 209: 57–66.
- 4. MR imaging and spectroscopy of brain development. Magn. Reson. Imag. Clin. N. Am. 2001; 6: 1–18.
- 5, , , , , , , . Early detection of regional cerebral ischemia in cats: comparison of diffusion- and T2-weighted MRI and spectroscopy. Magn. Reson. Med. 1990; 14: 330–346.Direct Link:
- 6, , , . Fast magnetic resonance diffusion-weighted imaging of acute human stroke. Neurology 1992; 42: 1717–1723.
- 7, , , , , . Diagnosis of acute cerebral infarction: Comparison of CT and MR imaging. Am. J. Neuroradiol. 1990; 12: 611–620.
- 8, . How much of neonatal encephalopathy is due to birth asphyxia? Am. J. Dis. Child. 1991; 145: 1325–1331.
- 9, , , , , , , . Periventricular white matter injury in the premature infant is followed by reduced cerebral cortical gray matter volume at term. Ann. Neurol. 1999; 46: 755–760.Direct Link:
- 10, , , . Correlation of rapid changes in the average water diffusion constant and the concentrations of lactate and ATP breakdown products during global ischemia in cat brain. Magn. Reson. Med. 1995; 34: 343–352.Direct Link:
- 11, . Diffusion weighting by the trace of the diffusion tensor within a single scan. Magn. Reson. Med. 1995; 33: 41–52.Direct Link:
- 12, . Orientation-independent diffusion imaging without tensor diagonalization: Anisotropy definitions based on physical attributes of the diffusion ellipsoid. J. Magn. Reson. Imag. 1999; 9: 804–813.Direct Link:
- 13, . Selecting an appropriate anisotropy index for displaying diffusion tensor imaging data with improved contrast and sensitivity. Magn. Reson. Med. 2000; 44: 117–121.Direct Link:
- 14Basser P, Jones DK. Diffusion-tensor MRI: Theory, experimental design, and data analysis. NMR Biomed. 2002; 15: 456–467.
- 15, , , . : Precision, accuracy and flow effects. NMR Biomed. 1995; 8: 307–332.Direct Link:
- 16, , , , , , . Normal brain maturation during childhood: Developmental trends characterized with diffusion-tensor MR imaging. Radiology 2001; 221: 349–358.
- 17, , , , . Changes in brain water diffusion during childhood. Neuroradiology 1999; 41: 929–934.
- 18, , , , . Diffusion tensor MR imaging of the human brain. Radiology 1996; 201: 637–648.
- 19, , , , , , , . Quantitative diffusion-tensor anisotropy brain MR imaging: normative human data and anatomic analysis. Radiology 1999; 212: 770–784.
- 20, . Selective measurement of white matter and gray matter diffusion trace values in normal human brain. Med. Phys. 1998; 25: 2237–2241.
- 21, , , , , , , , . Quantitative comparison of intrabrain diffusion in adults and preterm and term neonates and infants. Am. J. Roentgenol. 2000; 174: 1643–1649.
- 22, , , . Absolute quantitation of diffusion constants in human stroke. Stroke 1997; 28: 483–490.
- 23, , . Nutrition and the Developing Nervous System. Mosby: St Louis, MO, 1975.
- 24, , , , . Myelination and organization of the frontal white matter in children: a diffusion tensor MRI study. Neuroreport 1999; 10: 2817–2821.
- 25, , , , , , , , , . Evaluation of diffusion anisotropy during human cortical grey matter development. Proceedings of ISMRM, 8th Annual Meeting and Exhibition, 2000; 591.
- 26, , , , . Timing of changes on diffusion tensor imaging following brain injury in full-term infants. Ann. Neurol. 1998; 44: 551.
- 27, , , . Sequence of central nervous system myelination in human infancy. I. An autopsy study of myelination. J. Neuropathol. Exp. Neurol. 1987; 46: 283–301.
- 28Beaulieu C. The basis of anisotropic water diffusion in the nervous system. NMR Biomed. 2002; 15: 435–455.
- 29, , . Comparative MR imaging study of brain maturation in kittens with T1, T2, and the trace of the diffusion tensor. Radiology 1999; 210: 133–142.
- 30, , , , , , , . Anisotropic water diffusion in white and gray matter of the neonatal piglet brain before and after transient hypoxia-ischaemia. Magn. Reson. Imag. 1997; 15: 433–440.
- 31, , , , , , . Diffusion tensor imaging of the developing mouse brain. Magn. Reson. Med. 2001; 46: 18–23.Direct Link:
- 32. Ontogenesis of the pyramidal cell of the mammalian neocortex and developmental cytoarchitectonics: a unifying theory. J. Comp. Neurol. 1992; 321: 223–240.Direct Link:
- 33Mori S, van Zijl PCM. Fiber racking: Principles and strategies. NMR Biomed. 2002; 15: 468–480.
- 34. Neurology of the Newborn. W.B. Saunders: Philadelphia, PA, 2001.
- 35, , . Oxidative metabolism, apoptosis and perinatal brain injury. Brain Pathol. 1999; 9: 93–117.Direct Link:
- 36, . Molecular mechanisms of ischemic brain damage: Ca2+-related events. In: Cerebrovascular Diseases, PlumF, PulsinelliW (eds). New York: Raven Press, 1999.
- 37, , . Free radicals and brain damage in the newborn. Biol. Neonate 2001; 79: 180–186.
- 38, . Excitatory amino acids contribute to the pathogenesis of perinatal hypoxic-ischemic brain injury. Brain Pathol. 1992; 2: 235–243.Direct Link:
- 39, , , , , . Cytokines and perinatal brain injury. Neurochem. Int. 1997; 30: 375–383.
- 40, , , . Neonatal cytokines and coagulation factors in children with cerebral palsy. Ann. Neurol. 1998; 44: 665–675.Direct Link:
- 41, . Periventricular leukomalacia of infancy. Arch. Neurol. 1962; 7: 386–410.
- 42, . Advanced magnetic resonance imaging techniques in perinatal brain injury. Biol. Neonate 2001; 80: 7–14.
- 43
- 44. White matter injury in the preterm infant: An important determination of abnormal neurodevelopment outcome. Early Hum. Devl. 1998; 53: 99–120.
- 45
- 46, . Is periventricular leucomalacia a result of hypoxic-ischaemic injury? Hypocapnia and the preterm brain. Biol. Neonate 2001; 79: 194–200.
- 47, , , , , . Water diffusion and acute stroke. Magn. Reson. Med. 1994; 31: 154–163.Direct Link:
- 48, , , , . Early detection of cerebral infarction and hypoxic ischemic encephalopathy in neonates using diffusion-weighted magnetic resonance imaging. Neuropediatrics 1994; 25: 172–175.
- 49, , , . Evaluation of extra- and intracellular apparent diffusion in normal and globally ischemic rat brain via 19F NMR. Magn. Reson. Med. 1998; 40: 1–13.Direct Link:
- 50, , . Evaluation of intracellular diffusion in rat brain via133Cs NMR. Magn. Reson. Med. 1996; 35: 329–335.
- 51, , , . Alteration of intracellular metabolite diffusion in rat brain in vivo during ischemia and reperfusion. Stroke 1995; 26: 1930–1933.
- 52, , , . Diffusion of metabolites in normal and ischemic rat brain measured by localized 1H MRS. Magn. Reson. Med. 1996; 36: 914–922.Direct Link:
- 53, , , , , , , . Discrimination between different types of white matter edema with diffusion-weighted MR imaging. J. Magn. Reson. Imag. 1993; 3: 863–868.Direct Link:
- 54, , , , , , , , , . A reversible posterior leukoencephalopathy syndrome. New Engl. J. Med. 1996; 334: 494–500.
- 55, , , , , , . Posterior leukoencephalopathy without severe hypertension: utility of diffusion-weighted MRI. Neurology 1998; 51: 1369–1376.
- 56, . Reversible posterior leukoencephalopathy syndrome: evaluation with diffusion-tensor MR imaging. Radiology 2001; 219: 756–765.
- 57, , , , , . In vivo1H MR spectroscopic imaging and diffusion weighted MRI in experimental hydrocephalus. Magn. Reson. Med. 1998; 40: 832–839.Direct Link:
- 58, , , , . Increased self-diffusion of brain water in hydrocephalus measured by MR imaging. Acta Radiol. 1994; 35: 514–519.
- 59, , , , , . . Diffusion tensor imaging in neonatal post hemorrhagic hydrocephalus. Proceedings of ISMRM, 9th Annual Meeting and Exhibition, 2001; 1556.
- 60, , , , , , , , , . A model to predict the histopathology of human stroke using diffusion and T2-weighted magnetic resonance imaging. Stroke 1995; 26: 1983–1989.
- 61, , , , , , . Reversal of acute apparent diffusion coefficient abnormalities and delayed neuronal death following transient focal cerebral ischemia in rats. Ann. Neurol. 1999; 46: 333–342.Direct Link:
- 62, , , , , , , . Ischemic stroke: effects of etiology and patient age on the time course of the core apparent diffusion coefficient. Radiology 2001; 221: 27–34.
- 63, , . Neonatal hypoxic-ischemic encephalopathy: Detection with diffusion- weighted MR imaging. Am. J. Neuroradiol. 2000; 21: 1490–1496.
- 64, , , , , , , , . Early detection of periventricular leukomalacia by diffusion-weighted magnetic resonance imaging techniques. J. Pediatr. 1999; 134: 631–634.
- 65, , , . Quantitative apparent diffusion coefficient measurements in term neonates for early detection of hypoxic-ischemic brain injury: Initial experience. Radiology 2001; 218: 825–833.
- 66, , , , . Direct, longitudinal comparison of (1)H and (23)Na MRI after transient focal cerebral ischemia. Stroke 2001; 32: 925–932.
- 67, , , , , , Diffusion-negative stroke: A report of two cases. Am. J. Neuroradiol. 1999; 20: 1876–1880.
- 68, , , , . Perinatal asphyxia: MR findings in the first 10 days. Am. J. Neuroradiol. 1995; 16: 427–438.
- 69, , , , , , , . MR imaging of anisotropically restricted diffusion in the brain of neonates and infants. J. Comput. Assist. Tomogr. 1991; 15: 188–198.
- 70, , , , , , . Microstructure of temporo-parietal white matter as a basis for reading ability: evidence from diffusion tensor magnetic resonance imaging. Neuron 2000; 25: 493–500.
- 71, , , , , , . Water diffusion changes in wallerian degeneration and their dependence on white matter architecture. Neuroimage 2001; 13: 1174–1185.
- 72. Brain injury in the premature infant—current concepts. Prev. Med. 1994; 23: 638–645.
- 73, , , , , , , , . Microstructural brain development after perinatal cerebral white matter injury assessed by diffusion tensor magnetic resonance imaging. Pediatrics 2001; 107: 455–460.

1099-1492/asset/olbannercenter.jpg?v=1&s=f1d7cac966b2d80ea4dae4fe6b7d32766ad703b8)