Applications of diffusion-weighted and diffusion tensor MRI to white matter diseases – a review

Authors

  • Mark A. Horsfield,

    Corresponding author
    1. Division of Medical Physics, University of Leicester, Leicester Royal Infirmary, Leicester LE1 5WW, UK
    • Division of Medical Physics, University of Leicester, Leicester Royal Infirmary, Leicester LE1 5WW, UK
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  • Derek K. Jones

    1. Section for Old Age Psychiatry, Institute of Psychiatry, Denmark Hill, London SE5 8AF, UK
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Abstract

This paper reviews the current applications of diffusion-weighted and diffusion tensor MRI in diseases of the brain white matter. The contribution that diffusion-weighted imaging has made to our understanding of white matter diseases is critically appraised. The quantitative nature of diffusion MRI is one of its major attractions; however, this is offset by the more advanced hardware required to collect diffusion-weighted images reliably, and the more complex processing to produce quantitative parametric diffusion images. With the now common availability of scanners equipped to perform echo-planar imaging, the acquisition of diffusion tensor images is sure to become more widespread and routine. Copyright © 2002 John Wiley & Sons, Ltd.

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