Skin sodium measured with 23Na MRI at 7.0 T (pages 54–62)
Peter Linz, Davide Santoro, Wolfgang Renz, Jan Rieger, Anjuli Ruehle, Jan Ruff, Michael Deimling, Natalia Rakova, Dominik N. Muller, Friedrich C. Luft, Jens Titze and Thoralf Niendorf
Article first published online: 18 OCT 2014 | DOI: 10.1002/nbm.3224
This work demonstrates the feasibility of submillimeter in-plane spatial resolution 23Na MRI in skin at clinically acceptable acquisition times at 7.0 T. Intra-subject variability of human skin Na+ content in the volunteer population was <10.3%. An age-dependent increase in skin Na+ content was observed (r = 0.78). Assigning Na+ stores with 23Na MRI techniques could be improved at 7.0 T compared with current 3.0-T technology.