Get access

Symptom cluster and physical activity in relapsing-remitting multiple sclerosis

Authors

  • Robert W. Motl,

    Corresponding author
    1. Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign 350 Freer Hall, Urbana, Illinois 61801
    • Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign 350 Freer Hall, Urbana, Illinois 61801.
    Search for more papers by this author
    • Associate Professor.

  • Madeline Weikert,

    1. Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign 350 Freer Hall, Urbana, Illinois 61801
    Search for more papers by this author
    • Research Assistant.

  • Yoojin Suh,

    1. Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign 350 Freer Hall, Urbana, Illinois 61801
    Search for more papers by this author
    • Doctoral Student.

  • Deirdre Dlugonski

    1. Department of Kinesiology and Community Health, University of Illinois at Urbana-Champaign 350 Freer Hall, Urbana, Illinois 61801
    Search for more papers by this author
    • Doctoral Student.


Abstract

We compared the explanatory power of two symptom clusters that consisted of either three or five symptoms as correlates of physical activity in individuals with relapsing-remitting multiple sclerosis (RRMS; N = 218). The data were primarily analyzed using covariance modeling in Mplus 3.0. A symptom cluster of fatigue, depression, and pain had a moderate, negative relationship with physical activity, and this relationship was comparable in magnitude with a symptom cluster of fatigue, depression, pain, perceived cognitive dysfunction, and poor sleep quality. The relationships were attenuated after controlling for exercise history and neurological impairment. Such findings further support the consideration of a narrowly defined cluster of three symptoms as an independent correlate of physical activity in persons with RRMS. © 2010 Wiley Periodicals, Inc. Res Nurs Health 33:398–412, 2010

Get access to the full text of this article

Ancillary