Discloser: The authors have no conflict of interest.
Article first published online: 16 APR 2013
Copyright © 2012 The Obesity Society
Volume 21, Issue 3, pages E204–E210, March 2013
How to Cite
Tang, M., Armstrong, C. L.H., Leidy, H. J. and Campbell, W. W. (2013), Normal vs. high-protein weight loss diets in men: Effects on body composition and indices of metabolic syndrome. Obesity, 21: E204–E210. doi: 10.1002/oby.20078
Funding agencies: National Pork Board; American Egg Board-Egg Nutrition Center; Purdue Ingestive Behavior Research Center.
- Issue published online: 16 APR 2013
- Article first published online: 16 APR 2013
- Accepted manuscript online: 18 OCT 2012 12:59PM EST
- Manuscript Accepted: 21 AUG 2012
- Manuscript Revised: 27 JUN 2012
- Manuscript Received: 2 DEC 2011
- National Pork Board
- American Egg Board-Egg Nutrition Center
- Purdue Ingestive Behavior Research Center
This study assessed the effectiveness of a prescribed weight-loss diet with 0.8 versus 1.4 g protein·kg−1 day−1 on changes in weight, body composition, indices of metabolic syndrome, and resting energy expenditure (REE) in overweight and obese men.
Design and Methods:
Men were randomized to groups that consumed diets containing 750 kcal day−1 less than daily energy needs for weight maintenance with either normal protein (NP, n = 21) or higher protein (HP, n = 22) content for 12 weeks. The macronutrient distributions of the NP and HP diets were 25:60:15, and 25:50:25 percent energy from fat, carbohydrate, and protein, respectively. Assessments were made pre and post intervention. The subjects were retrospectively subgrouped into overweight and obese groups.
Results and Conclusion:
Both diet groups lost comparable body weight and fat. The HP group lost less lean body mass than the NP group (−1.9 ± 0.3 vs. −3.0 ± 0.4 kg). The effects of protein and BMI status on lean body mass loss were additive. The reductions in total cholesterol, HDL-C, triacylglycerol, glucose, and insulin, along with LDL-C, total cholesterol-to-HDL-C ratio, and HOMA-IR, were not statistically different between NP and HP. Likewise, macronutrient distributions of the diet did not affect the reductions in REE, and blood pressure. In conclusion, energy restriction effectively improves multiple clinical indicators of cardiovascular health and glucose control, and consumption of a higher-protein diet and accomplishing weight loss when overweight versus obese help men preserve lean body mass over a short period of time.