Disclosure: The authors declared no conflict of interest.
Evaluation of cardiovascular risk factors, events, and costs across four BMI categories
Version of Record online: 26 JUL 2013
Copyright © 2012 The Obesity Society
Volume 21, Issue 6, pages 1284–1292, June 2013
How to Cite
Brixner, D.I., Bron, M., Bellows, B.K., Ye, X., Yu, J., Raparla, S. and Oderda, G.M. (2013), Evaluation of cardiovascular risk factors, events, and costs across four BMI categories. Obesity, 21: 1284–1292. doi: 10.1002/oby.20215
Funding agencies: This research was supported by grant from Takeda Pharmaceuticals International, Inc.
Present address of J. Yu: Touro University California College of Pharmacy, 1310 Club Drive, Mare Island, Vallejo, CA 94592.
Present address of S. Raparla: HealthCore, Inc., 800 Delaware Avenue, Fifth Floor, Wilmington, DE 19801.
- Issue online: 26 JUL 2013
- Version of Record online: 26 JUL 2013
- Accepted manuscript online: 12 DEC 2012 11:17AM EST
- Manuscript Accepted: NOV 2012
- Manuscript Received: SEP 2011
The purpose of this study was to analyze the 1-year cost of cardiovascular (CV) events by body mass index (BMI) subgroups from a US employer health plan perspective.
Design and Methods
Patients aged 20-64 years from the GE Centricity Electronic Medical Record, National Health and Nutrition Examination Survey, and MarketScan databases were used to determine prevalence of risk factors (RFs) and CV events and 1-year costs. Risk factors included hypertension (HTN), diabetes, and hyperlipidemia (HLD) and CV events included myocardial infarction, angina, heart failure, and stroke. CV event costs were determined from claims by ICD-9 code in patients with overweight/obesity.
Of 220,136 patients identified in GE, BMI was 25-26.9 in 19.4%, 27-29.9 in 30.4%, 30-34.9 in 27.9%, and ≥35 in 22.3%. Patients with diabetes, HTN, and HLD increased with BMI from 1.8% (25-26.9) to 11.4% (≥35) in males and 1.1% to 6.8% in females. Prevalence of CV events increased from 0.1% with no RFs up to 10.2% with multiple RFs. The average 1-year cost per patient increased from $1122 to $2383 as BMI increased.
Patients with higher BMI values had an increased prevalence of RFs and CV events, which lead to higher average 1-year costs.