Funding agencies: This work was supported by “Conselleria de Educación de la Generalitat Valenciana” [BEST/2012/257]; Spanish Ministry of Education [EX-2010-1008]; National Institutes of Health [AG06945, HL62508, R21DK088195]; and in part by an unrestricted research grant from The Coca-Cola Company. The content is solely the responsibility of the authors and does not necessarily represent the official views of the funding institutions.
Body adiposity index and all-cause and cardiovascular disease mortality in men
Article first published online: 29 MAY 2013
Copyright © 2013 The Obesity Society
Volume 21, Issue 9, pages 1870–1876, September 2013
How to Cite
Moliner-Urdiales, D., Artero, E. G., Lee, D.-c., España-Romero, V., Sui, X. and Blair, S. N. (2013), Body adiposity index and all-cause and cardiovascular disease mortality in men. Obesity, 21: 1870–1876. doi: 10.1002/oby.20399
Conflicts of interest statement: The authors declared no conflict of interest.
- Issue published online: 23 SEP 2013
- Article first published online: 29 MAY 2013
- Accepted manuscript online: 20 MAR 2013 02:49AM EST
- Manuscript Accepted: 14 JAN 2013
- Manuscript Received: 20 NOV 2012
To evaluate the association of body adiposity index (BAI) with all-cause and cardiovascular disease (CVD) mortality risk.
Design and Methods
The current analysis comprised 19,756 adult men who enrolled in the Aerobics Centre Longitudinal Study and completed a baseline examination during 1988-2002. All-cause and CVD mortality was registered till December 31, 2003.
During an average follow-up of 8.3 years (163,844 man-years), 353 deaths occurred (101 CVD deaths). Age- and examination year-adjusted hazard ratios (HRs) and 95% confidence intervals (95% CIs) for all-cause mortality risk were higher for men with high values of BMI (HR = 1.63, 95% CI = 1.19-2.23), waist circumference (1.55, 1.22-1.96), and percentage of body fat (%BF) (1.36, 1.04-1.31), but not for men with high values of BAI (1.28, 0.98-1.66). The HRs for CVD mortality risks were higher for men with high values in all adiposity measures (HRs ranged from 1.73 to 2.06). Most of these associations, however, became nonsignificant after adjusting for multiple confounders including cardiorespiratory fitness.
BAI is not a better predictor of all-cause and CVD mortality risk than BMI, waist circumference, or %BF.