• 1
    Pan XR, Li GW, Hu YH, et al. Effects of diet and exercise in preventing NIDDM in people with impaired glucose tolerance. The Da Qing IGT and Diabetes Study. Diabetes Care 1997;20:537-544.
  • 2
    Uusitupa M, Lindi V, Louheranta A, Salopuro T, Lindstrom J, Tuomilehto J. Long-term improvement in insulin sensitivity by changing lifestyles of people with impaired glucose tolerance: 4-year results from the Finnish Diabetes Prevention Study. Diabetes 2003;52:2532-2538.
  • 3
    Slentz CA, Tanner CJ, Bateman LA, et al. Effects of exercise training intensity on pancreatic beta-cell function. Diabetes Care 2009;32:1807-1811.
  • 4
    Tjonna AE, Lee SJ, Rognmo O, et al. Aerobic interval training versus continuous moderate exercise as a treatment for the metabolic syndrome: a pilot study. Circulation 2008;118:346-354.
  • 5
    Newsom SA, Schenk S, Thomas KM, et al. Energy deficit after exercise augments lipid mobilization but does not contribute to the exercise-induced increase in insulin sensitivity. J Appl Physiol 2010;108:554-560.
  • 6
    Melanson EL, Gozansky WS, Barry DW, Maclean PS, Grunwald GK, Hill JO. When energy balance is maintained, exercise does not induce negative fat balance in lean sedentary, obese sedentary, or lean endurance-trained individuals. J Appl Physiol 2009;107:1847-1856.
  • 7
    Solomon TP, Haus JM, Kelly KR, et al. Randomized trial on the effects of a 7-d low-glycemic diet and exercise intervention on insulin resistance in older obese humans. Am J Clin Nutr 2009;90:1222-1229.
  • 8
    Solomon TP, Haus JM, Kelly KR, et al. A low-glycemic index diet combined with exercise reduces insulin resistance, postprandial hyperinsulinemia, and glucose-dependent insulinotropic polypeptide responses in obese, prediabetic humans. Am J Clin Nutr 2010;92:1359-1368.
  • 9
    Kelly KR, Haus JM, Solomon TP, et al. A low-glycemic index diet and exercise intervention reduces TNF(alpha) in isolated mononuclear cells of older, obese adults. J Nutr 2011;141:1089-1094.
  • 10
    Haus JM, Solomon TP, Lu L, et al. Intramyocellular lipid content and insulin sensitivity are increased following a short-term low-glycemic index diet and exercise intervention. Am J Physiol Endocrinol Metab 2011;301:E511-E516.
  • 11
    Kirwan JP, O'Gorman D, Evans WJ. A moderate glycemic meal before endurance exercise can enhance performance. J Appl Physiol 1998;84:53-59.
  • 12
    Kirwan JP, Cyr-Campbell D, Campbell WW, Scheiber J, Evans WJ. Effects of moderate and high glycemic index meals on metabolism and exercise performance. Metabolism 2001;50:849-855.
  • 13
    Stevenson EJ, Williams C, Mash LE, Phillips B, Nute ML. Influence of high-carbohydrate mixed meals with different glycemic indexes on substrate utilization during subsequent exercise in women. Am J Clin Nutr 2006;84:354-360.
  • 14
    Stevenson EJ, Astbury NM, Simpson EJ, Taylor MA, Macdonald IA. Fat oxidation during exercise and satiety during recovery are increased following a low-glycemic index breakfast in sedentary women. J Nutr 2009;139:890-897.
  • 15
    Febbraio MA, Keenan J, Angus DJ, Campbell SE, Garnham AP. Preexercise carbohydrate ingestion, glucose kinetics, and muscle glycogen use: effect of the glycemic index. J Appl Physiol 2000;89:1845-1851.
  • 16
    Wee SL, Williams C, Gray S, Horabin J. Influence of high and low glycemic index meals on endurance running capacity. Med Sci Sports Exerc 1999;31:393-399.
  • 17
    Clapp JF, Lopez B. Low- versus high-glycemic index diets in women: effects on caloric requirement, substrate utilization and insulin sensitivity. Metab Syndr Relat Disord 2007;5:231-242.
  • 18
    Scazzina F, Del RD, Benini L, et al. The effect of breakfasts varying in glycemic index and glycemic load on dietary induced thermogenesis and respiratory quotient. Nutr Metab Cardiovasc Dis 2011;21:121-125.
  • 19
    Diaz EO, Galgani JE, Aguirre CA, Atwater IJ, Burrows R. Effect of glycemic index on whole-body substrate oxidation in obese women. Int J Obes (Lond) 2005;29:108-114.
  • 20
    Diaz EO, Galgani JE, Aguirre CA. Glycaemic index effects on fuel partitioning in humans. Obes Rev 2006;7:219-226.
  • 21
    O'Leary VB, Marchetti CM, Krishnan RK, Stetzer BP, Gonzalez F, Kirwan JP. Exercise-induced reversal of insulin resistance in obese elderly is associated with reduced visceral fat. J Appl Physiol 2006;100:1584-1589.
  • 22
    Weir JB. New methods for calculating metabolic rate with special reference to protein metabolism. J Physiol 1949;109:1-9.
  • 23
    Frayn KN. Calculation of substrate oxidation rates in vivo from gaseous exchange. J Appl Physiol 1983;55:628-634.
  • 24
    Khuu A, Ren J, Dimitrov I, et al. Orientation of lipid strands in the extracellular compartment of muscle: effect on quantitation of intramyocellular lipids. Magn Reson Med 2009;61:16-21.
  • 25
    Isken F, Klaus S, Petzke KJ, Loddenkemper C, Pfeiffer AF, Weickert MO. Impairment of fat oxidation under high- vs. low-glycemic index diet occurs before the development of an obese phenotype. Am J Physiol Endocrinol Metab 2010;298:E287-E295.
  • 26
    Scribner KB, Pawlak DB, Aubin CM, Majzoub JA, Ludwig DS. Long-term effects of dietary glycemic index on adiposity, energy metabolism, and physical activity in mice. Am J Physiol Endocrinol Metab 2008;295:E1126-E1131.
  • 27
    Bouche C, Rizkalla SW, Luo J, et al. Five-week, low-glycemic index diet decreases total fat mass and improves plasma lipid profile in moderately overweight nondiabetic men. Diabetes Care 2002;25:822-828.
  • 28
    Pittas AG, Das SK, Hajduk CL, et al. A low-glycemic load diet facilitates greater weight loss in overweight adults with high insulin secretion but not in overweight adults with low insulin secretion in the CALERIE Trial. Diabetes Care 2005;28:2939-2941.
  • 29
    Wee SL, Williams C, Tsintzas K, Boobis L. Ingestion of a high-glycemic index meal increases muscle glycogen storage at rest but augments its utilization during subsequent exercise. J Appl Physiol 2005;99:707-714.
  • 30
    Coyle EF, Jeukendrup AE, Wagenmakers AJ, Saris WH. Fatty acid oxidation is directly regulated by carbohydrate metabolism during exercise. Am J Physiol 1997;273( 2 Pt 1):E268-E275.
  • 31
    Goodpaster BH, Katsiaras A, Kelley DE. Enhanced fat oxidation through physical activity is associated with improvements in insulin sensitivity in obesity. Diabetes 2003;52:2191-2197.
  • 32
    Nicklas BJ, Rogus EM, Goldberg AP. Exercise blunts declines in lipolysis and fat oxidation after dietary-induced weight loss in obese older women. Am J Physiol 1997;273( 1 Pt 1):E149-E155.
  • 33
    Solomon TP, Sistrun SN, Krishnan RK et al. Exercise and diet enhance fat oxidation and reduce insulin resistance in older obese adults. J Appl Physiol 2008;104:1313-1319.