Author contributions: DJ and JW conceived and carried out experiments, OF and MB analyzed the data. All authors were involved in writing the paper and had final approval of the submitted and published versions.
High Caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women
Version of Record online: 2 JUL 2013
Copyright © 2013 The Obesity Society
Volume 21, Issue 12, pages 2504–2512, December 2013
How to Cite
Jakubowicz, D., Barnea, M., Wainstein, J. and Froy, O. (2013), High Caloric intake at breakfast vs. dinner differentially influences weight loss of overweight and obese women. Obesity, 21: 2504–2512. doi: 10.1002/oby.20460
Conflict of interest: No authors have any competing interests.
- Issue online: 3 DEC 2013
- Version of Record online: 2 JUL 2013
- Accepted manuscript online: 20 MAR 2013 02:17AM EST
- Manuscript Accepted: 5 MAR 2013
- Manuscript Received: 31 JAN 2013
Few studies examined the association between time-of-day of nutrient intake and the metabolic syndrome. Our goal was to compare a weight loss diet with high caloric intake during breakfast to an isocaloric diet with high caloric intake at dinner.
Design and Methods
Overweight and obese women (BMI 32.4 ± 1.8 kg/m2) with metabolic syndrome were randomized into two isocaloric (∼1400 kcal) weight loss groups, a breakfast (BF) (700 kcal breakfast, 500 kcal lunch, 200 kcal dinner) or a dinner (D) group (200 kcal breakfast, 500 kcal lunch, 700 kcal dinner) for 12 weeks.
The BF group showed greater weight loss and waist circumference reduction. Although fasting glucose, insulin, and ghrelin were reduced in both groups, fasting glucose, insulin, and HOMA-IR decreased significantly to a greater extent in the BF group. Mean triglyceride levels decreased by 33.6% in the BF group, but increased by 14.6% in the D group. Oral glucose tolerance test led to a greater decrease of glucose and insulin in the BF group. In response to meal challenges, the overall daily glucose, insulin, ghrelin, and mean hunger scores were significantly lower, whereas mean satiety scores were significantly higher in the BF group.
High-calorie breakfast with reduced intake at dinner is beneficial and might be a useful alternative for the management of obesity and metabolic syndrome.