Funding agencies: This work was supported by grants from the Canadian Diabetes Association and the Canadian Institutes of Health Research (to AK). LNF was funded by a postdoctoral fellowships from Novo Nordisk A/S. TEJ was funded by a Danish Research Council postdoctoral fellowship. SRC was supported by a Mitacs fellowship. Human muscle biopsy collection was supported by Deutsche Forschungsgemeinschaft, Clinical Research group “Atherobesity” (KFO152; BL 833/1-1). We thank Dr. Assaf Rudich for his initial stimulus of this study and Zhi Liu for excellent technical assistance.Additional Supporting Information may be found in the online version of this article.
Pro-Inflammatory macrophages increase in skeletal muscle of high fat-Fed mice and correlate with metabolic risk markers in humans
Article first published online: 16 OCT 2013
© 2013 The Obesity Society
Volume 22, Issue 3, pages 747–757, March 2014
How to Cite
Fink, L. N., Costford, S. R., Lee, Y. S., Jensen, T. E., Bilan, P. J., Oberbach, A., Blüher, M., Olefsky, J. M., Sams, A. and Klip, A. (2014), Pro-Inflammatory macrophages increase in skeletal muscle of high fat-Fed mice and correlate with metabolic risk markers in humans. Obesity, 22: 747–757. doi: 10.1002/oby.20615
Disclosure: LNF and AS are employed by Novo Nordisk and own stocks. All other authors declared no conflict of interest.
Author Contributions: LNF designed the study, researched and analyzed data and wrote the manuscript; SRC researched and analyzed data and contributed to discussion and editing of manuscript; YSL, TEJ, AO, and MB researched data and contributed to discussion; PJB analyzed data and contributed to discussion and editing of manuscript; JMO and AS contributed to discussion and editing of manuscript; AK designed the study, analyzed data and wrote the manuscript. All authors approved the submitted and published versions.
- Issue published online: 5 MAR 2014
- Article first published online: 16 OCT 2013
- Accepted manuscript online: 13 SEP 2013 02:36AM EST
- Manuscript Accepted: 4 SEP 2013
- Manuscript Revised: 8 AUG 2013
- Manuscript Received: 9 JUL 2013
- 17Genevestigator V3: a reference expression database for the meta-analysis of transcriptomes. Adv Bioinformatics 2008;420747., , , et al.