Helgi B. Schiöth and Christian Benedict contributed equally to this work.
Increased impulsivity in response to food cues after sleep loss in healthy young men
Version of Record online: 16 MAY 2014
Copyright © 2014 The Authors Obesity published by Wiley Periodicals, Inc. on behalf of The Obesity Society (TOS)
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
Volume 22, Issue 8, pages 1786–1791, August 2014
How to Cite
Cedernaes, J., Brandell, J., Ros, O., Broman, J.-E., Hogenkamp, P. S., Schiöth, H. B. and Benedict, C. (2014), Increased impulsivity in response to food cues after sleep loss in healthy young men. Obesity, 22: 1786–1791. doi: 10.1002/oby.20786
Funding agencies: The Swedish Brain Foundation, the Novo Nordisk Foundation, the Åke Wiberg Foundation, the Swedish Society for Sleep Research and Sleep Medicine, and the Swedish Research Council. Dr. Cedernaes is the recipient of a grant from the Swedish Brain Foundation. The funders had no role in study design, data collection and analysis, or preparation of the manuscript.
Disclosure: The authors declare no conflicts of interest.
Author contribution: JC and CB designed the study; JC and CB wrote the protocol; JC, JB, and OR collected the data; and JC, JB, JEB, PH, HBS, and CB conducted the analyses. All authors contributed to and have approved the final manuscript.
- Issue online: 26 JUL 2014
- Version of Record online: 16 MAY 2014
- Manuscript Accepted: 30 APR 2014
- Manuscript Received: 16 MAR 2014
- acute total sleep deprivation;
- cognitive control;
- food intake;
- selective attention;
- shift work
To investigate whether acute total sleep deprivation (TSD) leads to decreased cognitive control when food cues are presented during a task requiring active attention, by assessing the ability to cognitively inhibit prepotent responses.
Fourteen males participated in the study on two separate occasions in a randomized, crossover within-subject design: one night of TSD versus normal sleep (8.5 hours). Following each nighttime intervention, hunger ratings and morning fasting plasma glucose concentrations were assessed before performing a go/no-go task.
Following TSD, participants made significantly more commission errors when they were presented “no-go” food words in the go/no-go task, as compared with their performance following sleep (+56%; P<0.05). In contrast, response time and omission errors to “go” non-food words did not differ between the conditions. Self-reported hunger after TSD was increased without changes in fasting plasma glucose. The increase in hunger did not correlate with the TSD-induced commission errors.
Our results suggest that TSD impairs cognitive control also in response to food stimuli in healthy young men. Whether such loss of inhibition or impulsiveness is food cue-specific as seen in obesity—thus providing a mechanism through which sleep disturbances may promote obesity development—warrants further investigation.