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Original Paper

A fatty acid-binding protein 7/RXRβ pathway enhances survival and proliferation in triple-negative breast cancer†

  1. Rong-Zong Liu1,
  2. Kathryn Graham1,
  3. Darryl D Glubrecht1,
  4. Raymond Lai2,
  5. John R Mackey1,
  6. Roseline Godbout1,*

Article first published online: 18 APR 2012

DOI: 10.1002/path.4001

Issue

The Journal of Pathology

The Journal of Pathology

Volume 228, Issue 3, pages 310–321, November 2012

Additional Information

How to Cite

Liu, R.-Z., Graham, K., Glubrecht, D. D., Lai, R., Mackey, J. R. and Godbout, R. (2012), A fatty acid-binding protein 7/RXRβ pathway enhances survival and proliferation in triple-negative breast cancer. J. Pathol., 228: 310–321. doi: 10.1002/path.4001

Author Information

  1. 1

    Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada, T6G 1Z2

  2. 2

    Department of Lab Medicine and Pathology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada, T6G 1Z2

*Roseline Godbout, Department of Oncology, University of Alberta, Cross Cancer Institute, 11560 University Avenue, Edmonton, Alberta, Canada, T6G 1Z2. E-mail: rgodbout@ualberta.ca

  1. †

    No conflicts of interest were declared.

Publication History

  1. Issue published online: 12 OCT 2012
  2. Article first published online: 18 APR 2012
  3. Accepted manuscript online: 9 FEB 2012 07:22AM EST
  4. Manuscript Accepted: 29 JAN 2012
  5. Manuscript Revised: 18 JAN 2012
  6. Manuscript Received: 7 DEC 2011

Funded by

  • Alberta Cancer Research Institute
  • Canadian Breast Cancer Foundation

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FilenameFormatSizeDescription
path4001-sup-0001-FigureS1.pdfPDF document198KSupporting Information: Figure S1. Kaplan–Meier survival curves of patients with tumours expressing low or high RXRβ (A) or RXRα (B) mRNA levels.
path4001-sup-0002-FigureS2.pdfPDF document226KSupporting Information: Figure S2. (A) mRNA levels of FABP3 (left) and FABP4 (right) in triple-negative and non-triple-negative breast tumours based on gene microarray signal intensity (values were log-transformed). Significance level (p) of Student's t-test of means is indicated. (B) Kaplan–Meier survival curves of breast cancer patients with tumours expressing low or high levels of FABP3 (left) or FABP4 (right). Cut-off values were determined by ROC analysis.
path4001-sup-0003-TableS1.pdfPDF document80KSupporting Information: Table S1. Clinicopathological associations of FABP7 in human breast cancers.

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View Full Article with Supporting Information (HTML) Get PDF (549K)