• Please log in or register to access this feature.

Original Paper

You have full text access to this OnlineOpen article

Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes†

  1. David J McBride1,‡,*,
  2. Dariush Etemadmoghadam2,3,‡,*,
  3. Susanna L Cooke1,4,‡,*,
  4. Kathryn Alsop2,5,
  5. Joshy George2,5,
  6. Adam Butler1,
  7. Juok Cho1,
  8. Danushka Galappaththige1,
  9. Chris Greenman1,
  10. Karen D Howarth6,
  11. King W Lau1,
  12. Charlotte K Ng4,
  13. Keiran Raine1,
  14. Jon Teague1,
  15. David C Wedge1,
  16. Australian Ovarian Cancer Study Group2,
  17. Xavier Caubit7,
  18. Michael R Stratton1,
  19. James D Brenton4,
  20. Peter J Campbell1,
  21. P Andrew Futreal1,§,
  22. David DL Bowtell2,5,8,§,*

Article first published online: 6 JUN 2012

DOI: 10.1002/path.4042

Issue

The Journal of Pathology

The Journal of Pathology

Volume 227, Issue 4, pages 446–455, August 2012

Additional Information

How to Cite

McBride, D. J., Etemadmoghadam, D., Cooke, S. L., Alsop, K., George, J., Butler, A., Cho, J., Galappaththige, D., Greenman, C., Howarth, K. D., Lau, K. W., Ng, C. K., Raine, K., Teague, J., Wedge, D. C., Cancer Study Group, A. O., Caubit, X., Stratton, M. R., Brenton, J. D., Campbell, P. J., Futreal, P. A. and Bowtell, D. D. (2012), Tandem duplication of chromosomal segments is common in ovarian and breast cancer genomes. J. Pathol., 227: 446–455. doi: 10.1002/path.4042

Author Information

  1. 1

    Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, Cambridge, UK

  2. 2

    Cancer Genomics and Genetics, Peter MacCallum Cancer Centre, Melbourne, Australia

  3. 3

    Department of Pathology, University of Melbourne, Australia

  4. 4

    Cancer Research UK Cambridge Research Institute, Cambridge, UK

  5. 5

    Department of Biochemistry and Molecular Biology, University of Melbourne, Parkville, Australia

  6. 6

    Hutchison/MRC Research Centre and Department of Pathology, University of Cambridge, UK

  7. 7

    Developmental Biology Institute of Marseille-Luminy (IBDML), UMR 6216, CNRS-Inserm-Université de la Méditerranée, France

  8. 8

    Sir Peter MacCallum Department of Oncology, University of Melbourne, Australia

  1. ‡

    Joint first authors.

  2. §

    Joint senior authors.

*Cancer Genomics and Genetics, Peter MacCallum Cancer Centre, Melbourne, Australia.

  1. †

    No conflicts of interest were declared.

  2. ‡

    Joint first authors.

  3. §

    Joint senior authors.

Publication History

  1. Issue published online: 10 JUL 2012
  2. Article first published online: 6 JUN 2012
  3. Accepted manuscript online: 18 APR 2012 06:45AM EST
  4. Manuscript Accepted: 7 APR 2012
  5. Manuscript Revised: 6 APR 2012
  6. Manuscript Received: 25 JAN 2012

SEARCH

SEARCH BY CITATION

ARTICLE TOOLS

View Full Article with Supporting Information (HTML) Get PDF (1210K)
FilenameFormatSizeDescription
path_4042_sm_suppinfofigs1.pdf118KSupporting Information: Figure S1. Analysis of TSHZ3 gene expression in AOCS and TCGA datasets.
path_4042_sm_suppinfotabs1.xls22KSupporting Information: Table S1. Sample details.
path_4042_sm_suppinfotabs2.xls205KSupporting Information: Table S2. Summary of somatic rearrangements found in 13 ovarian cancers.
path_4042_sm_suppinfotabs3.xls76KSupporting Information: Table S3. Breakpoints in known genes.
path_4042_sm_suppinfotabs4.xls18KSupporting Information: Table S4. Primer sequences.
path_4042_sm_suppinfotabs5.doc43KSupporting Information: Table S5. Tumour cell content predicted by ASCAT and PICNIC.
path_4042_sm_suppinfosm.doc126KSupporting Information: Supplementary methods
path_4042_sm_suppinfo.doc34KSupporting Information: Legend to Figure S1

Please note: Wiley-Blackwell is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.

View Full Article with Supporting Information (HTML) Get PDF (1210K)