No conflicts of interest were declared.
Inflammation, wound repair, and fibrosis: reassessing the spectrum of tissue injury and resolution
Version of Record online: 12 DEC 2012
Copyright © 2012 Pathological Society of Great Britain and Ireland. Published by John Wiley & Sons, Ltd.
The Journal of Pathology
Special Issue: Inflammation, Wound Repair & Fibrosis
Volume 229, Issue 2, pages 141–144, January 2013
How to Cite
White, E. S. and Mantovani, A. R. (2013), Inflammation, wound repair, and fibrosis: reassessing the spectrum of tissue injury and resolution. J. Pathol., 229: 141–144. doi: 10.1002/path.4126
- Issue online: 12 DEC 2012
- Version of Record online: 12 DEC 2012
- Accepted manuscript online: 24 OCT 2012 04:52AM EST
- Manuscript Accepted: 5 OCT 2012
- Manuscript Received: 3 OCT 2012
- Manuscript Revised: 3 OCT 2012
- wound healing
Estimates from various disease-specific registries suggest that chronic inflammatory and fibrotic disorders affect a large proportion of the world's population, yet therapies for these conditions are largely ineffective. Recent advances in our collective understanding of mechanisms underlying both physiological and pathological repair of tissue injury are informing new clinical approaches to deal with various human inflammatory and fibrotic diseases. This 2013 Annual Review Issue of The Journal of Pathology offers an up-to-date glimpse of ongoing research in the fields of inflammation, wound healing, and tissue fibrosis, and highlights novel pathways and mechanisms that may be exploited to provide newer, more effective treatments to patients worldwide suffering from these conditions.