The Journal of Pathology

Cover image for Vol. 225 Issue 1

September 2011

Volume 225, Issue 1

Pages 1–156

  1. Invited Commentaries

    1. Top of page
    2. Invited Commentaries
    3. Original Papers
  2. Original Papers

    1. Top of page
    2. Invited Commentaries
    3. Original Papers
    1. Aberrant succination of proteins in fumarate hydratase-deficient mice and HLRCC patients is a robust biomarker of mutation status (pages 4–11)

      Chiara Bardella, Mona El-Bahrawy, Norma Frizzell, Julie Adam, Nicola Ternette, Emine Hatipoglu, Kimberley Howarth, Linda O'Flaherty, Ian Roberts, Gareth Turner, Jennifer Taylor, Konstantinos Giaslakiotis, Valentine M Macaulay, Adrian L Harris, Ashish Chandra, Heli J Lehtonen, Virpi Launonen, Lauri A Aaltonen, Christopher W Pugh, Radu Mihai, David Trudgian, Benedikt Kessler, John W Baynes, Peter J Ratcliffe, Ian P Tomlinson and Patrick J Pollard

      Article first published online: 1 JUN 2011 | DOI: 10.1002/path.2932

    2. Using next-generation sequencing for the diagnosis of rare disorders: a family with retinitis pigmentosa and skeletal abnormalities (pages 12–18)

      Kasmintan A Schrader, Alireza Heravi-Moussavi, Paula J Waters, Janine Senz, James Whelan, Gavin Ha, Patrice Eydoux, Torsten Nielsen, Barry Gallagher, Arusha Oloumi, Niki Boyd, Bridget A Fernandez, Terry-Lynn Young, Steven JM Jones, Martin Hirst, Sohrab P Shah, Marco A Marra, Jane Green and David G Huntsman

      Article first published online: 25 JUL 2011 | DOI: 10.1002/path.2941

    3. A ΔRaf1–ER-inducible oncogenic zebrafish liver cell model identifies hepatocellular carcinoma signatures (pages 19–28)

      Shuning He, SF Gabby Krens, Huiqing Zhan, Zhiyuan Gong, Pancras CW Hogendoorn, Herman P Spaink and B Ewa Snaar-Jagalska

      Article first published online: 8 JUL 2011 | DOI: 10.1002/path.2936

    4. Functional characterization of EMSY gene amplification in human cancers (pages 29–42)

      Paul M Wilkerson, Konstantin J Dedes, Daniel Wetterskog, Alan Mackay, Maryou B Lambros, Marthe Mansour, Jessica Frankum, Christopher J Lord, Rachael Natrajan, Alan Ashworth and Jorge S Reis-Filho

      Article first published online: 7 JUL 2011 | DOI: 10.1002/path.2944

    5. MicroRNA profiling for the identification of cancers with unknown primary tissue-of-origin (pages 43–53)

      Manuela Ferracin, Massimo Pedriali, Angelo Veronese, Barbara Zagatti, Roberta Gafà, Eros Magri, Maria Lunardi, Gardenia Munerato, Giulia Querzoli, Iva Maestri, Linda Ulazzi, Italo Nenci, Carlo M Croce, Giovanni Lanza, Patrizia Querzoli and Massimo Negrini

      Article first published online: 1 JUN 2011 | DOI: 10.1002/path.2915

    6. Deficient brain insulin signalling pathway in Alzheimer's disease and diabetes (pages 54–62)

      Ying Liu, Fei Liu, Inge Grundke-Iqbal, Khalid Iqbal and Cheng-Xin Gong

      Article first published online: 19 MAY 2011 | DOI: 10.1002/path.2912

    7. Expression of hypoxia-associated proteins in sporadic medullary thyroid cancer is associated with desmoplastic stroma reaction and lymph node metastasis and may indicate somatic mutations in the VHL gene (pages 63–72)

      Oskar Koperek, Oliver Bergner, Bettina Pichlhöfer, Felicitas Oberndorfer, Johannes A Hainfellner, Klaus Kaserer, Reinhard Horvat, Adrian L Harris, Bruno Niederle and Peter Birner

      Article first published online: 1 JUN 2011 | DOI: 10.1002/path.2926

    8. Down-regulation of spinophilin in lung tumours contributes to tumourigenesis (pages 73–82)

      Sonia Molina-Pinelo, Irene Ferrer, Carmen Blanco-Aparicio, Sandra Peregrino, Maria Dolores Pastor, Juan Alvarez-Vega, Rocio Suarez, Mar Verge, Juan J Marin, Javier Hernandez-Losa, Santiago Ramon y Cajal, Luis Paz-Ares and Amancio Carnero

      Article first published online: 19 MAY 2011 | DOI: 10.1002/path.2905

    9. Insulin-like growth factor-1 receptor inhibition overcomes gefitinib resistance in mucinous lung adenocarcinoma (pages 83–95)

      Amandine Hurbin, Marie Wislez, Benoît Busser, Martine Antoine, Corine Tenaud, Nathalie Rabbe, Sandrine Dufort, Florence de Fraipont, Denis Moro-Sibilot, Jacques Cadranel, Jean-Luc Coll and Elisabeth Brambilla

      Article first published online: 19 MAY 2011 | DOI: 10.1002/path.2897

    10. Discovery of a novel tumour metastasis-promoting gene, NVM-1 (pages 96–105)

      Wilko Thiele, Natalia Novac, Sigrun Mink, Caroline Schreiber, Diana Plaumann, Johannes Fritzmann, Natascha Cremers, Melanie Rothley, Christian Schwager, Thomas Regiert, Peter E. Huber, Ulrike Stein, Peter Schlag, Jürgen Moll, Amir Abdollahi and Jonathan P. Sleeman

      Article first published online: 8 JUL 2011 | DOI: 10.1002/path.2924

    11. Identification of abrogated pathways in fallopian tube epithelium from BRCA1 mutation carriers (pages 106–117)

      Sophia HL George, James Greenaway, Anca Milea, Victoria Clary, Sanjeev Shaw, Monika Sharma, Carl Virtanen and Patricia A Shaw

      Article first published online: 8 JUL 2011 | DOI: 10.1002/path.2927

    12. Nephrin expression in adult rodent central nervous system and its interaction with glutamate receptors (pages 118–128)

      Min Li, Silvia Armelloni, Masami Ikehata, Alessandro Corbelli, Marzia Pesaresi, Novella Calvaresi, Laura Giardino, Deborah Mattinzoli, Francesca Nisticò, Serena Andreoni, Aldamaria Puliti, Roberto Ravazzolo, Gianluigi Forloni, Piergiorgio Messa and Maria Pia Rastaldi

      Article first published online: 1 JUN 2011 | DOI: 10.1002/path.2923

    13. Cystogenic potential of CD133+ progenitor cells of human polycystic kidneys (pages 129–141)

      Raquel Carvalhosa, Ilaria Deambrosis, Paola Carrera, Chiara Pasquino, Francesca Rigo, Maurizio Ferrari, Fedele Lasaponara, Andrea Ranghino, Luigi Biancone, Giuseppe Segoloni, Benedetta Bussolati and Giovanni Camussi

      Article first published online: 27 JUN 2011 | DOI: 10.1002/path.2920

    14. Interleukin-6 signalling regulates vascular endothelial growth factor-C synthesis and lymphangiogenesis in human oral squamous cell carcinoma (pages 142–150)

      Satoru Shinriki, Hirofumi Jono, Mitsuharu Ueda, Kazutoshi Ota, Tomoko Ota, Takanao Sueyoshi, Yuichi Oike, Mutsuko Ibusuki, Akimitsu Hiraki, Hideki Nakayama, Masanori Shinohara and Yukio Ando

      Article first published online: 25 JUN 2011 | DOI: 10.1002/path.2935

    15. Osteoclast formation and function in pigmented villonodular synovitis (pages 151–156)

      Richard Taylor, Takesh G Kashima, Helen Knowles, C L Max H Gibbons, Duncan Whitwell and Nicholas A Athanasou

      Article first published online: 27 JUN 2011 | DOI: 10.1002/path.2937

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