The Journal of Pathology

Cover image for Vol. 227 Issue 1

May 2012

Volume 227, Issue 1

Pages 1–129

  1. Invited Commentaries

    1. Top of page
    2. Invited Commentaries
    3. Original Papers
  2. Original Papers

    1. Top of page
    2. Invited Commentaries
    3. Original Papers
    1. Gene amplification of ESR1 in breast cancers—fact or fiction? A fluorescence in situ hybridization and multiplex ligation-dependent probe amplification study (pages 8–16)

      Akishi Ooi, Masafumi Inokuchi, Shinichi Harada, Johji Inazawa, Ryousuke Tajiri, Seiko Sawada- Kitamura, Hiroko Ikeda, Hiroko Kawashima and Yoh Dobashi

      Article first published online: 2 FEB 2012 | DOI: 10.1002/path.3974

    2. A whole-genome massively parallel sequencing analysis of BRCA1 mutant oestrogen receptor-negative and -positive breast cancers (pages 29–41)

      Rachael Natrajan, Alan Mackay, Maryou B Lambros, Britta Weigelt, Paul M Wilkerson, Elodie Manie, Anita Grigoriadis, Roger A'Hern, Petra van der Groep, Iwanka Kozarewa, Tatiana Popova, Odette Mariani, Samra Turajlic, Simon J Furney, Richard Marais, Daniel-Nava Rodruigues, Adriana C Flora, Patty Wai, Vidya Pawar, Simon McDade, Jason Carroll, Dominique Stoppa-Lyonnet, Andrew R Green, Ian O Ellis, Charles Swanton, Paul van Diest, Olivier Delattre, Christopher J Lord, William D Foulkes, Anne Vincent-Salomon, Alan Ashworth, Marc Henri Stern and Jorge S Reis-Filho

      Article first published online: 23 FEB 2012 | DOI: 10.1002/path.4003

    3. Genomic and mutational profiling of ductal carcinomas in situ and matched adjacent invasive breast cancers reveals intra-tumour genetic heterogeneity and clonal selection (pages 42–52)

      Lucia Hernandez, Paul M Wilkerson, Maryou B Lambros, Adriana Campion-Flora, Daniel Nava Rodrigues, Arnaud Gauthier, Cecilia Cabral, Vidya Pawar, Alan Mackay, Roger A'Hern, Caterina Marchiò, Jose Palacios, Rachael Natrajan, Britta Weigelt and Jorge S Reis-Filho

      Article first published online: 21 MAR 2012 | DOI: 10.1002/path.3990

    4. Integrated genome and transcriptome sequencing identifies a novel form of hybrid and aggressive prostate cancer (pages 53–61)

      Chunxiao Wu, Alexander W Wyatt, Anna V Lapuk, Andrew McPherson, Brian J McConeghy, Robert H Bell, Shawn Anderson, Anne Haegert, Sonal Brahmbhatt, Robert Shukin, Fan Mo, Estelle Li, Ladan Fazli, Antonio Hurtado-Coll, Edward C Jones, Yaron S Butterfield, Faraz Hach, Fereydoun Hormozdiari, Iman Hajirasouliha, Paul C Boutros, Robert G Bristow, Steven JM Jones, Martin Hirst, Marco A Marra, Christopher A Maher, Arul M Chinnaiyan, S Cenk Sahinalp, Martin E Gleave, Stanislav V Volik and Colin C Collins

      Article first published online: 21 MAR 2012 | DOI: 10.1002/path.3987

    5. One virus, one lesion—individual components of CIN lesions contain a specific HPV type (pages 62–71)

      Wim Quint, David Jenkins, Anco Molijn, Linda Struijk, Miekel van de Sandt, John Doorbar, Johann Mols, Christine Van Hoof, Karin Hardt, Frank Struyf and Brigitte Colau

      Article first published online: 17 FEB 2012 | DOI: 10.1002/path.3970

    6. Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney (pages 72–80)

      Elaine O'Meara, Deirdre Stack, Cheng-Han Lee, A Julian Garvin, Thomas Morris, Pedram Argani, Jeong S Han, Jenny Karlsson, David Gisselson, Ivo Leuschner, Manfred Gessler, Norbert Graf, Jonathan A Fletcher and Maureen J O'Sullivan

      Article first published online: 17 FEB 2012 | DOI: 10.1002/path.3985

    7. Non-junctional human desmoglein 3 acts as an upstream regulator of Src in E-cadherin adhesion, a pathway possibly involved in the pathogenesis of pemphigus vulgaris (pages 81–93)

      Siu Man Tsang, Louise Brown, Kuang Lin, Li Liu, Kim Piper, Edel A O'Toole, Richard Grose, Ian R Hart, David R Garrod, Farida Fortune and Hong Wan

      Article first published online: 17 FEB 2012 | DOI: 10.1002/path.3982

    8. Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis (pages 94–105)

      Daniel H Madsen, Henrik J Jürgensen, Signe Ingvarsen, Maria C Melander, Ben Vainer, Kristoffer L Egerod, Andreas Hald, Birgitte Rønø, Charlotte A Madsen, Thomas H Bugge, Lars H Engelholm and Niels Behrendt

      Article first published online: 17 FEB 2012 | DOI: 10.1002/path.3981

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    10. Calpain 2-dependent IκBα degradation mediates CPT-11 secondary resistance in colorectal cancer xenografts (pages 118–129)

      Nina Fenouille, Sebastien Grosso, SU Yunchao, Didier Mary, Rodolphe Pontier-Bres, Véronique Imbert, Dorota Czerucka, François-Xavier Caroli-Bosc, Jean-François Peyron and Patricia Lagadec

      Article first published online: 9 FEB 2012 | DOI: 10.1002/path.3034