The study was performed at The Children's Hospital of Philadelphia.
Effects of physical therapy intervention for children with acute lymphoblastic leukemia†
Version of Record online: 15 DEC 2003
Copyright © 2003 Wiley-Liss, Inc.
Pediatric Blood & Cancer
Volume 42, Issue 2, pages 127–133, February 2004
How to Cite
Marchese, V. G., Chiarello, L. A. and Lange, B. J. (2004), Effects of physical therapy intervention for children with acute lymphoblastic leukemia. Pediatr. Blood Cancer, 42: 127–133. doi: 10.1002/pbc.10481
- Issue online: 9 JAN 2004
- Version of Record online: 15 DEC 2003
- Manuscript Accepted: 14 NOV 2003
- Manuscript Received: 12 MAY 2003
- Maternal and Child Health Bureau. Grant Number: MCJ-429506
- physical therapy
The purpose of this study was to examine the effects of physical therapy intervention in children with acute lymphoblastic leukemia (ALL).
Twenty-eight children aged 4–15 years were randomly assigned to an intervention or control group. The intervention group received five sessions of physical therapy and was instructed to perform an individualized home exercise program consisting of ankle dorsiflexion stretching, lower extremity strengthening, and aerobic exercise.
After 4 months children who received physical therapy intervention had significantly improved ankle dorsiflexion active range of motion and knee extension strength (P < 0.01). Differences were not found between the two groups for any of the other dependent variables.
Physical therapy intervention for children with ALL receiving maintenance chemotherapy improved two body functions important for normal gait. Physical therapy programs initiated earlier in treatment and with greater emphasis on endurance activities may also improve stamina and quality of life (QOL). © 2003 Wiley-Liss, Inc.