Veno-occlusive disease of the liver in a child after chemotherapy for brain tumor
Version of Record online: 29 NOV 2005
Copyright © 2005 Wiley-Liss, Inc.
Pediatric Blood & Cancer
Volume 46, Issue 4, pages 521–523, April 2006
How to Cite
Elli, M., Güçlü Pınarlı, F., Daǧdemir, A. and Acar, S. (2006), Veno-occlusive disease of the liver in a child after chemotherapy for brain tumor. Pediatr. Blood Cancer, 46: 521–523. doi: 10.1002/pbc.20338
- Issue online: 15 FEB 2006
- Version of Record online: 29 NOV 2005
- Manuscript Accepted: 17 DEC 2004
- Manuscript Received: 4 NOV 2004
- veno-occlusive disease;
Veno-occlusive disease (VOD) of the liver is a life-threatening state generally occurring as a complication of bone marrow transplantation or chemotherapy for Wilms' tumor. Veno-occlusive disease after standard dose chemotherapy in malignancies other than Wilms' tumor is rare and only a few cases have been published in children. We report a 19 month-old-girl with medulloblastoma who experienced fatal VOD of liver after only one course of chemotherapy including carboplatin, vincristine and CCNU for medulloblastoma. As our knowledge, this is the first report of VOD after standard dose chemotherapy for brain tumor in childhood. Pediatr Blood Cancer 2006,46:521–523. © 2005 Wiley-Liss, Inc.