Radiotherapy in the multimodal treatment of extrarenal extracranial malignant rhabdoid tumors
Article first published online: 19 JUL 2006
Copyright © 2006 Wiley-Liss, Inc.
Pediatric Blood & Cancer
Volume 50, Issue 1, pages 167–169, January 2008
How to Cite
Puri, D. R., Meyers, P. A., Kraus, D. H., LaQuaglia, M. P., Wexler, L. H. and Wolden, S. L. (2008), Radiotherapy in the multimodal treatment of extrarenal extracranial malignant rhabdoid tumors. Pediatr. Blood Cancer, 50: 167–169. doi: 10.1002/pbc.20947
- Issue published online: 19 NOV 2007
- Article first published online: 19 JUL 2006
- Manuscript Accepted: 30 MAY 2006
- Manuscript Received: 21 FEB 2006
- malignant rhabdoid tumor;
Extrarenal extracranial malignant rhabdoid tumors (MRT) are extremely rare and typically lethal. No consensus exists on an optimal treatment approach, and, in particular, the role of radiation therapy (RT) is poorly defined. We report on three children who underwent multimodality treatment including surgery, chemotherapy (CMT), and RT. Two of these patients are alive and without evidence of disease 6½ and 7 years after diagnosis and one has expired. Our limited experience suggests that RT in the setting of CMT and surgery has the potential to prolong survival with acceptable toxicity, but outcomes are inconsistent and further study is necessary. Pediatr Blood Cancer 2008;50:167–169. © 2006 Wiley-Liss, Inc.