Idiopathic thrombocytopenic purpura in childhood: Controversies and solutions
Article first published online: 24 AUG 2006
Copyright © 2006 Wiley-Liss, Inc.
Pediatric Blood & Cancer
Special Issue: 2nd Intercontinental Childhood ITP Study Group (ICIS) Expert Meeting on “Critical Issues and Future Research of ITP”, September 16–18, 2006, Yverdon, Switzerland
Volume 47, Issue S5, pages 650–652, 15 October 2006
How to Cite
Kühne, T. (2006), Idiopathic thrombocytopenic purpura in childhood: Controversies and solutions. Pediatr. Blood Cancer, 47: 650–652. doi: 10.1002/pbc.20973
- Issue published online: 24 AUG 2006
- Article first published online: 24 AUG 2006
- Manuscript Received: 20 JUN 2006
- Manuscript Accepted: 20 JUN 2006
Idiopathic thrombocytopenic purpura (ITP) is a bleeding disorder in patients who are otherwise healthy and present with thrombocytopenia with normal red cells and leukocytes. ITP is a diagnosis of exclusion and is in origin heterogeneous. The unknown etiology and the lack of clinical data from controlled prospective studies are reasons for controversies in diagnosis and management. Study endpoints traditionally include the velocity of platelet increase after drug intervention or observation, although a rapid elevation of the platelet count is of questionable clinical value. Evaluation of other endpoints is needed. Pediatr Blood Cancer 2006;47:650–652. © 2006 Wiley-Liss, Inc.