Pediatric thyroid cancer arising after treatment for pleuropulmonary blastoma

Authors

  • Takaharu Oue MD,

    Corresponding author
    1. Department of Surgery, Division of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan
    • Department of Surgery, Division of Pediatric Surgery, Osaka University Graduate School of Medicine, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan.
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  • Masami Inoue MD,

    1. Department of Hematology and Oncology, Osaka Medical Center and Research Institute for Maternal & Child Health, Izumi, Osaka, Japan
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  • Akio Kubota MD,

    1. Department of Pediatric Surgery, Osaka Medical Center and Research Institute for Maternal & Child Health, Izumi, Osaka, Japan
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  • Yuko Kuwae MD,

    1. Department of Pathology, Osaka Medical Center and Research Institute for Maternal & Child Health, Izumi, Osaka, Japan
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  • Keisei Kawa MD

    1. Department of Hematology and Oncology, Osaka Medical Center and Research Institute for Maternal & Child Health, Izumi, Osaka, Japan
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Abstract

A 3-year-old female presented with a large tumor occupying the right thoracic space. Open biopsy revealed the pathological diagnosis of pleuropulmonary blastoma. After the first-line chemotherapy, the patient underwent surgical resection, then two courses of high-dose chemotherapy. Three years later, follicular carcinoma of the right thyroid lobe was found, so a right hemithyroidectomy was performed. Five months later, the thyroid tumor recurred. The remaining thyroid lobe was completely excised and radioiodine therapy was administered. The patient has remained tumor-free for 3 years. The etiology and treatment of the uncommon combination of pleuropulmonary blastoma and thyroid carcinoma is discussed. Pediatr Blood Cancer 2008;50:901–902. © 2007 Wiley-Liss, Inc.

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