Prenatal supplementation with multivitamins and the incidence of pediatric cancers: Clinical and methodological considerations

Authors

  • Y. Ingrid Goh HBSc,

    Corresponding author
    1. Motherisk Program, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Canada
    2. Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada
    • The Hospital for Sick Children, Division of Clinical Pharmacology and Toxicology, 555 University Avenue, Toronto, Ontario, Canada M5G 1X8.
    Search for more papers by this author
  • Gideon Koren MD

    1. Motherisk Program, Division of Clinical Pharmacology and Toxicology, The Hospital for Sick Children, Toronto, Canada
    2. Department of Pharmaceutical Sciences, University of Toronto, Toronto, Canada
    3. Ivey Chair Molecular Toxicology, Department of Medicine, University of Western Ontario, London, Ontario, Canada
    Search for more papers by this author

Abstract

Cancer is the second leading cause of death in children. Research has been undertaken to identify risk factors associated with pediatric cancers. Nevertheless one single cause has not been isolated. Recent studies have suggested that prenatal multivitamin consumption may be associated with the prevention of pediatric cancers. It has been shown previously that prenatal multivitamin ingestion is associated with a decrease in congenital anomalies. The following review summarizes the available knowledge associating prenatal multivitamin consumption with the prevention of pediatric cancers. Pediatr Blood Cancer 2008;50:487–489. © 2007 Wiley-Liss, Inc.

Ancillary