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Review Article
Body composition, exercise and energy expenditure in survivors of acute lymphoblastic leukaemia
Article first published online: 6 DEC 2007
DOI: 10.1002/pbc.21411
Copyright © 2007 Wiley-Liss, Inc.
Issue
1545-5017/asset/cover.gif?v=1&s=a75210663ec4a312a5bd8e3022f1967dde569328 "Pediatric Blood & Cancer")
Pediatric Blood & Cancer
Special Issue: Nutrition and Cancer in Children The Second International Workshop, Puebla, Mexico, November 1–5, 2006
Supplement: Puebla Workshop Supplement
Volume 50, Issue Supplement 2, pages 456–461, February 2008
Additional Information
How to Cite
Warner, J. T. (2008), Body composition, exercise and energy expenditure in survivors of acute lymphoblastic leukaemia. Pediatric Blood & Cancer, 50: 456–461. doi: 10.1002/pbc.21411
Publication History
- Issue published online: 6 DEC 2007
- Article first published online: 6 DEC 2007
- Manuscript Received: 17 SEP 2007
- Manuscript Accepted: 17 SEP 2007
- Abstract
- Article
- References
- Cited By
Keywords:
- body composition;
- exercise;
- physical fitness;
- energy expenditure
Abstract
Survivors of acute lymphoblastic leukaemia (ALL) are recognised to become overweight and this seems to worsen with increasing length of follow up. Increases in body fat appear to be more marked in girls than in boys and in those who have received prophylactic cranial irradiation. Physiological responses to exercise, both at submaximal and maximal levels, are different in ALL survivors compared to controls. Heart rate appears to be increased at low intensity exercise, possibly to maintain adequate cardiac output. Maximal aerobic capacity is reduced, signifying a lower level of physical fitness. Total daily energy expenditure (TDEE) under free living conditions appears limited due to low participation in physical activity. Associations exist between measures of energy expenditure and body fat, but whether these are cause or effect has yet to proven. Pediatr Blood Cancer 2008;50:456–461. © 2007 Wiley-Liss, Inc.