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Keywords:

  • census;
  • epidemiology;
  • infections;
  • leukemia;
  • population mixing

Abstract

There is growing evidence that some chronic diseases are caused, or promoted, by infectious disease. ‘Population mixing’ has been used as a proxy for the range and dose of infectious agents circulating in a community. Given the speculation over the role of population mixing in many chronic diseases, we review the various methods used for measuring population mixing, and provide a classification of these. We recommend that authors fulfill two criteria in publications: measures are demonstrably associated with the putative risk factors for which population-mixing is acting as a proxy and fundamental characteristics of the chosen measures are clearly defined. Pediatr Blood Cancer 2008;51:155–160. © 2008 Wiley-Liss, Inc.