Conflict of interest: nothing to declare.
Response of NF1-related plexiform neurofibroma to High-Dose Carboplatin†
Article first published online: 11 NOV 2010
Copyright © 2010 Wiley-Liss, Inc.
Pediatric Blood & Cancer
Volume 56, Issue 3, pages 488–490, March 2011
How to Cite
Hummel, T., Anyane-Yeboa, A., Mo, J., Towbin, A. and Weiss, B. (2011), Response of NF1-related plexiform neurofibroma to High-Dose Carboplatin. Pediatr. Blood Cancer, 56: 488–490. doi: 10.1002/pbc.22827
- Issue published online: 10 JAN 2011
- Article first published online: 11 NOV 2010
- Manuscript Accepted: 17 AUG 2010
- Manuscript Received: 15 SEP 2009
- neurofibromatosis type 1;
- plexiform neurofibroma
Plexiform neurofibromas (PN) are a hallmark of neurofibromatosis type 1 (NF1). These large nerve tumors can be disfiguring and surgery is the only known standard therapy. Surgical intervention may be suboptimal due to the diffuse nature of PN. Here, we present a case in which we describe the use of high-dose carboplatin to treat the patient's testicular seminoma which resulted in the decrease in size of a PN in a patient with NF1. Pediatr Blood Cancer 2011;56:488–490. © 2010 Wiley-Liss, Inc.