Senior Specialist, Paediatric Oncologist.
Carboplatin-based chemotherapy and surgery: A cost effective treatment strategy for malignant extracranial germ cell tumours in the developing world†
Article first published online: 4 MAR 2011
Copyright © 2011 Wiley-Liss, Inc.
Pediatric Blood & Cancer
Volume 57, Issue 1, pages 172–174, 15 July 2011
How to Cite
Hendricks, M., Davidson, A., Pillay, K., Desai, F. and Millar, A. (2011), Carboplatin-based chemotherapy and surgery: A cost effective treatment strategy for malignant extracranial germ cell tumours in the developing world. Pediatr. Blood Cancer, 57: 172–174. doi: 10.1002/pbc.23055
Conflict of interest: Nothing to report.
- Issue published online: 9 MAY 2011
- Article first published online: 4 MAR 2011
- Manuscript Accepted: 4 JAN 2011
- Manuscript Received: 15 JUL 2010
- carboplatin-based chemotherapy;
- malignant extracranial germ cell tumours
Nineteen children with malignant extracranial germ cell tumours (MEGCT), were treated at our institution with a combination of carboplatin-based chemotherapy and surgery from 1992 to 2008. Seventeen are long term survivors. Chemotherapy was administered on an outpatient basis and required no monitoring of GFR or auditory function. There were no deaths from toxicity or infection. Blood product use was low. Carboplatin-based therapy achieved excellent results in our patient population and constitutes more than a US $1,800 saving per patient compared to regimens containing cisplatin. This has application in resource limited settings. Pediatr Blood Cancer 2011;57:172–174. © 2011 Wiley-Liss, Inc.