This article was published online 3/21/2011. An error was subsequently identified. This notice is included in the online and print versions to indicate that both have been corrected 7/25/2011.
Article first published online: 21 MAR 2011
Copyright © 2011 Wiley Periodicals, Inc.
Pediatric Blood & Cancer
Volume 58, Issue 3, pages 390–394, March 2012
How to Cite
Youlden, D. R., Baade, P. D., Valery, P. C., Hassall, T. E., Ward, L. J., Green, A. C. and Aitken, J. F. (2012), Area-based differentials in childhood cancer incidence in Australia, 1996–2006. Pediatr. Blood Cancer, 58: 390–394. doi: 10.1002/pbc.23115
Conflict of interest: None.
- Issue published online: 10 JAN 2012
- Article first published online: 21 MAR 2011
- Manuscript Accepted: 7 FEB 2011
- Manuscript Received: 21 DEC 2010
- Cancer Council Queensland
- National Health and Medical Research Council Public Health Training Grant
- childhood cancer;
- socioeconomic status
International studies examining the association between the incidence of childhood cancer and characteristics of the area in which the patient lives have generally reported inconsistent patterns. Area-based differentials in childhood cancer throughout Australia have not been previously published at a national level.
Population-based information from the Australian Paediatric Cancer Registry was used to identify all children aged 0- to 14-years old diagnosed with invasive cancer or intracranial and intraspinal tumors of benign or uncertain behavior between 1996 and 2006. Age-standardized incidence rates per million children per year and the corresponding incidence rate ratios were calculated, categorized by remoteness of residence and an area-based index of socioeconomic disadvantage. Results were also stratified by the most common types of childhood cancer.
There was a significant, decreasing gradient in the incidence of childhood cancer as remoteness of residence increased. Children living in remote or very remote areas were 21% less likely to be diagnosed with cancer compared to children in major cities, mainly due to differences in the incidence of leukemias and lymphomas. This differential was no longer significant when only non-Indigenous children were considered. No clear relationship was found between incidence and socioeconomic status (SES) in contrast to similar earlier studies.
The findings by remoteness of residence are consistent with the lower incidence rates of cancer that are typically associated with Indigenous Australians. There is also a suggestion that the etiological factors associated with childhood leukemia and SES may have altered over time. Pediatr Blood Cancer 2012; 58: 390–394. © 2011 Wiley Periodicals, Inc.