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Should we still be focused on red cell hemoglobin F as the principal explanation for the salutary effect of hydroxyurea in sickle cell disease?

Authors

  • George B. Segel MD,

    Corresponding author
    1. Department of Pediatrics, University of Rochester Medical Center, Rochester, New York
    2. Department of Medicine, University of Rochester Medical Center, Rochester, New York
    • Department of Pediatrics, University of Rochester Medical Center, Box 777, 601 Elmwood Avenue, Rochester, NY 14642.
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  • William Simon PhD,

    1. Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York
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  • Marshall A. Lichtman MD

    1. Department of Medicine, University of Rochester Medical Center, Rochester, New York
    2. Department of Biochemistry and Biophysics, University of Rochester Medical Center, Rochester, New York
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