Conflict of interest: Nothing to declare.
Health-related quality of life in sickle cell disease: Past, present, and future†
Article first published online: 22 APR 2012
Copyright © 2012 Wiley Periodicals, Inc.
Pediatric Blood & Cancer
Volume 59, Issue 2, pages 377–385, August 2012
How to Cite
Panepinto, J. A. and Bonner, M. (2012), Health-related quality of life in sickle cell disease: Past, present, and future. Pediatr. Blood Cancer, 59: 377–385. doi: 10.1002/pbc.24176
- Issue published online: 11 JUN 2012
- Article first published online: 22 APR 2012
- Manuscript Received: 27 MAR 2012
- Manuscript Accepted: 27 MAR 2012
- health-related quality of life;
- sickle cell disease;
- well being
Health-related quality of life (HRQL) is defined as the patient's appraisal of how his/her well being and level of functioning, compared to the perceived ideal, are affected by individual health. The study of HRQL in children and adults with sickle cell disease (SCD) has begun to flourish. Given the devastating complications of the disease and other co-morbid factors patients experience that influence HRQL, it is increasingly important to understand HRQL. The focus of this critical review was to examine past and current research in HRQL in SCD where a validated instrument was used. In addition, future directions for HRQL in SCD are explored. Pediatr Blood Cancer 2012;59:377–385. © 2012 Wiley Periodicals, Inc.