Conflict of interest: Nothing to declare.
Clinical Practice Guidelines
SIOP-PODC recommendations for graduated-intensity treatment of retinoblastoma in developing countries†
Article first published online: 17 JAN 2013
Copyright © 2013 Wiley Periodicals, Inc.
Pediatric Blood & Cancer
Volume 60, Issue 5, pages 719–727, May 2013
How to Cite
Chantada, G., Luna-Fineman, S., Sitorus, R. S., Kruger, M., Israels, T., Leal-Leal, C., Bakhshi, S., Qaddoumi, I., Abramson, D. H., Doz, F. and SIOP-PODC graduated-intensity retinoblastoma guidelines writing committee (2013), SIOP-PODC recommendations for graduated-intensity treatment of retinoblastoma in developing countries. Pediatr. Blood Cancer, 60: 719–727. doi: 10.1002/pbc.24468
- Issue published online: 14 MAR 2013
- Article first published online: 17 JAN 2013
- Manuscript Accepted: 13 DEC 2012
- Manuscript Received: 7 NOV 2012
- Fund for Ophthalmic Knowledge, New York, NY, USA
- developing countries;
Retinoblastoma remains incurable in many regions of the world. The major obstacles to cure are delayed diagnosis, poor treatment compliance, and lack of evidence-based recommendations for clinical management. Although enucleation is curative for intraocular disease, in developing countries retinoblastoma is often diagnosed after the disease has disseminated beyond the eye. A SIOP-PODC committee generated guidelines for the clinical management of retinoblastoma in developing countries and developed a classification system based on the resources available in those settings. Recommendations are provided for staging and treatment of unilateral and bilateral retinoblastoma and counseling of families for whom compliance is an issue. Pediatr Blood Cancer 2013; 60: 719–727. © 2013 Wiley Periodicals, Inc.