CLL/SLL diagnosed in an adolescent

Authors

  • Marlise Luskin MD,

    Corresponding author
    1. Division of Hematology/Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
    • Correspondence to: Marlise Luskin, Division of Hematology/Oncology, Perelman School of Medicine at the University of Pennsylvania, 16 Penn Tower, 3400 Spruce St, Philadelphia, PA 19104.

      E-mail: marlise.luskin@uphs.upenn.edu

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  • Gerald Wertheim MD, PhD,

    1. Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    2. Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
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  • Jennifer Morrissette PhD, FACMG,

    1. Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
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  • Robert Daber PhD,

    1. Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
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  • Jaclyn Biegel PhD,

    1. Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
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  • Donna Wilmoth BA,

    1. Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
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  • Leslie Kersun MD, MS,

    1. Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
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  • Rebecca King MD,

    1. Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    2. Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
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  • Michele Paessler DO,

    1. Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
    2. Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
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  • Cara Simon PhD, RN, CPNP,

    1. Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
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  • Richard Aplenc MD, PhD,

    1. Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania
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  • Alison Loren MD, MS

    1. Division of Hematology/Oncology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania
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  • Conflict of interest: Nothing to report.
  • Marlise Luskin and Gerald Wertheim contributed equally to this work.

Abstract

Chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL) is a disease of older adults. Pediatric CLL/SLL is vanishingly rare in the literature. We present a case of CLL/SLL diagnosed in a 17-year-old male. The pathologic findings of this case were those of classic CLL/SLL with an ATM deletion, a characteristic genetic abnormality in CLL/SLL. Management guidelines for CLL/SLL are tailored to older adults making determination of the optimal therapy for this patient a unique challenge. Pediatr Blood Cancer 2014;61:1107–1110. © 2013 Wiley Periodicals, Inc.

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