The development of Moyamoya syndrome after proton beam therapy

Authors

  • Nathan T. Zwagerman MD,

    1. Department of Neurological Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
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  • Kimberly Foster MD,

    1. Department of Neurological Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
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  • Regina Jakacki MD,

    1. Department of Neurological Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
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  • Fazal H. Khan CMD,

    1. Department of Radiation Oncology, Francis H. Burr Proton Therapy Center, Massachusetts General Hospital, Boston, Massachusetts
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  • Torunn I. Yock MD, MCH,

    1. Department of Radiation Oncology, Francis H. Burr Proton Therapy Center, Massachusetts General Hospital, Boston, Massachusetts
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  • Stephanie Greene MD

    Corresponding author
    1. Department of Neurological Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania
    • Correspondence to: Stephanie Greene, Department of Neurological Surgery, Children's Hospital of Pittsburgh, University of Pittsburgh Medical Center, 4401 Penn Avenue, Pittsburgh, PA 15223.

      E-mail: Stephanie.greene@chp.edu

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  • Conflict of interest: Nothing to declare.

Abstract

The development of Moyamoya syndrome (MMS) after cranial irradiation for pediatric tumors has been well established. However, information on the development of MMS after proton beam radiotherapy is sparse. We present the case of a 2-year-old child who developed radiation-induced MMS after treatment with proton beam therapy. Pediatr Blood Cancer 2014; 61:1490–1492. © 2014 Wiley Periodicals, Inc.

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