Fetal magnetic resonance imaging (MRI) of ischemic brain injury
Article first published online: 20 AUG 2001
Copyright © 2001 John Wiley & Sons, Ltd.
Volume 21, Issue 9, pages 729–736, September 2001
How to Cite
de Laveaucoupet, J., Audibert, F., Guis, F., Rambaud, C., Suarez, B., Boithias-Guérot, C. and Musset, D. (2001), Fetal magnetic resonance imaging (MRI) of ischemic brain injury. Prenat. Diagn., 21: 729–736. doi: 10.1002/pd.135
- Issue published online: 20 AUG 2001
- Article first published online: 20 AUG 2001
- Manuscript Revised: 23 MAR 2001
- Manuscript Accepted: 8 MAR 2001
- Manuscript Received: 25 SEP 2000
- fetal brain;
- fetal brain;
- prenatal diagnosis
The aim of the present study was to demonstrate the usefulness of fetal magnetic resonance imaging (MRI) in ischemic brain injury. We report seven cases of fetal brain ischemia prenatally suspected on ultrasound (US) and confirmed by fetal MRI. Sonographic abnormalities included ventricular dilatation (n=3), microcephaly (n=1), twin pregnancy with in utero death of a twin and suspected cerebral lesion in the surviving co-twin (n=3). MRI was performed with a 1.0 T unit using half-Fourier acquisition single-shot turbo spin-echo (HASTE) sequences between 28 and 35 weeks of gestation. US and MRI images were compared with pathologic findings or postnatal imaging. MRI diagnosed hydranencephaly (n=1), porencephaly (n=2), multicystic encephalomalacia (n=2), unilateral capsular ischemia (n=1), corpus callosum and cerebral atrophy (n=1).
In comparison with US, visualization of fetal brain anomalies was superior with MRI. The present cases demonstrate that MRI is a valuable complementary means of investigation when a brain pathology is discovered or suspected during prenatal US. Copyright © 2001 John Wiley & Sons, Ltd.