Early second-trimester diagnosis of sirenomelia

Authors

  • M. M. Van Zalen-Sprock MD,

    Corresponding author
    1. Division of Prenatal Diagnosis, Department of Obstetrics and Gynecology, Free University Hospital, Amsterdam, The Netherlands
    • Division of Prenatal Diagnosis, Department of Obstetrics and Gynecology, Academisch Ziekenhuis Vrije Universiteit, P.O. Box 7057, 1007 MB Amsterdam, The Netherlands
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  • J. M. G. Van Vugt,

    1. Division of Prenatal Diagnosis, Department of Obstetrics and Gynecology, Free University Hospital, Amsterdam, The Netherlands
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  • J. J. Van Der Harten,

    1. Department of Pathology, Free University Hospital, Amsterdam, The Netherlands
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  • H. P. Van Geijn

    1. Division of Prenatal Diagnosis, Department of Obstetrics and Gynecology, Free University Hospital, Amsterdam, The Netherlands
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Abstract

Two cases of sirenomelia are described, detected in the 14th and 16th weeks of gestation by transvaginal ultrasonography. A hypothesis for the aetiology of sirenomelia and its associated anomalies is discussed.

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