Funding sources: None
Fetal aneuploidy screening by maternal plasma DNA sequencing: ‘False positive’ due to confined placental mosaicism
Article first published online: 27 NOV 2012
© 2012 John Wiley & Sons, Ltd.
Volume 33, Issue 2, pages 198–200, February 2013
How to Cite
Choi, H., Lau, T. K., Jiang, F. M., Chan, M. K., Zhang, H. Y., Lo, P. S. S., Chen, F., Zhang, L. and Wang, W. (2013), Fetal aneuploidy screening by maternal plasma DNA sequencing: ‘False positive’ due to confined placental mosaicism. Prenat. Diagn., 33: 198–200. doi: 10.1002/pd.4024
Conflicts of interest: The co-authors, Fuman Jiang, Mei Ki Chan, Hongyun Zhang, Fang Chen, Lei Zhang and Wei Wang are employees of BGI.
- Issue published online: 3 FEB 2013
- Article first published online: 27 NOV 2012
What's already known about this topic?
- Non-invasive prenatal testing by maternal plasma DNA sequencing is highly sensitive and specific in detecting fetal aneuploidies.
What does this study add?
- We report a case of ‘false positive’ result of NIPT because of confined placental mosaicism.